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P2X Purinoceptor 7 (P2Z Receptor or P2RX7) - Pipeline Review, H2 2017

Published: Jul, 2017 | Pages: 39 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)

P2X Purinoceptor 7 (P2Z Receptor or P2RX7) - Pipeline Review, H2 2017

Summary

According to the recently published report 'P2X Purinoceptor 7 - Pipeline Review, H2 2017'; P2X Purinoceptor 7 (P2Z Receptor or P2RX7) pipeline Target constitutes close to 9 molecules. Out of which approximately 9 molecules are developed by Companies. 

P2X Purinoceptor 7 (P2Z Receptor or P2RX7) - P2X purinoceptor 7 is a protein encoded by the P2RX7 gene. It acts as receptor for ATP that acts as a ligand-gated ion channel. It is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. 

The report 'P2X Purinoceptor 7 - Pipeline Review, H2 2017' outlays comprehensive information on the P2X Purinoceptor 7 (P2Z Receptor or P2RX7) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type; that are being developed by Companies / Universities.

It also reviews key players involved in P2X Purinoceptor 7 (P2Z Receptor or P2RX7) targeted therapeutics development with respective active and dormant or discontinued projects. Currently, The molecules developed by companies in Phase II, Phase I, Preclinical and Discovery stages are 1, 2, 5 and 1 respectively. Report covers products from therapy areas Central Nervous System, Immunology, Oncology, Gastrointestinal, Genetic Disorders, Metabolic Disorders and Musculoskeletal Disorders which include indications Neuropathic Pain, Inflammation, Multiple Sclerosis, Alzheimer's Disease, Autoimmune Disorders, Basal Cell Carcinoma (Basal Cell Epithelioma), Bipolar Disorder (Manic Depression), Charcot-Marie-Tooth Disease Type I A, Depression, Inflammatory Bowel Disease, Major Depressive Disorder, Mania, Muscular Dystrophy, Neurodegenerative Diseases, Osteoarthritis Pain, Psoriasis, Rheumatoid Arthritis, Solid Tumor, Systemic Lupus Erythematosus, Transplant Rejection, Type 1 Diabetes (Juvenile Diabetes) and Visceral Pain.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

- The report provides a snapshot of the global therapeutic landscape for P2X Purinoceptor 7 (P2Z Receptor or P2RX7)
- The report reviews P2X Purinoceptor 7 (P2Z Receptor or P2RX7) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources 
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages 
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities 
- The report reviews key players involved in P2X Purinoceptor 7 (P2Z Receptor or P2RX7) targeted therapeutics and enlists all their major and minor projects 
- The report assesses P2X Purinoceptor 7 (P2Z Receptor or P2RX7) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type 
- The report summarizes all the dormant and discontinued pipeline projects 
- The report reviews latest news and deals related to P2X Purinoceptor 7 (P2Z Receptor or P2RX7) targeted therapeutics

Reasons To Buy

- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage 
- Identify and understand the targeted therapy areas and indications for P2X Purinoceptor 7 (P2Z Receptor or P2RX7)
- Identify the use of drugs for target identification and drug repurposing
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies 
- Plan mergers and acquisitions effectively by identifying key players and it's most promising pipeline therapeutics
- Devise corrective measures for pipeline projects by understanding P2X Purinoceptor 7 (P2Z Receptor or P2RX7) development landscape 
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
 Table of Contents
List of Tables List of Figures Introduction Global Markets Direct Report Coverage P2X Purinoceptor 7 (P2Z Receptor or P2RX7) - Overview P2X Purinoceptor 7 (P2Z Receptor or P2RX7) - Therapeutics Development Products under Development by Stage of Development Products under Development by Therapy Area Products under Development by Indication Products under Development by Companies P2X Purinoceptor 7 (P2Z Receptor or P2RX7) - Therapeutics Assessment Assessment by Mechanism of Action Assessment by Route of Administration Assessment by Molecule Type P2X Purinoceptor 7 (P2Z Receptor or P2RX7) - Companies Involved in Therapeutics Development Affectis Pharmaceuticals AG Axxam SpA Biosceptre International Ltd Evotec AG Johnson & Johnson Medestea Research & Production SpA P2X Purinoceptor 7 (P2Z Receptor or P2RX7) - Drug Profiles AFC-5128 - Drug Profile Product Description Mechanism Of Action R&D Progress BIL-010t - Drug Profile Product Description Mechanism Of Action R&D Progress BIL-06v - Drug Profile Product Description Mechanism Of Action R&D Progress EVT-401 - Drug Profile Product Description Mechanism Of Action R&D Progress JNJ-47965567 - Drug Profile Product Description Mechanism Of Action R&D Progress JNJ-5446 - Drug Profile Product Description Mechanism Of Action R&D Progress Small Molecule to Antagonize P2X7 Receptor for Central Nervous System - Drug Profile Product Description Mechanism Of Action R&D Progress Small Molecules to Antagonize P2RX7 for CNS Disorders, Autoimmune Disorders and Inflammation - Drug Profile Product Description Mechanism Of Action R&D Progress WITH-1101 - Drug Profile Product Description Mechanism Of Action R&D Progress P2X Purinoceptor 7 (P2Z Receptor or P2RX7) - Dormant Products P2X Purinoceptor 7 (P2Z Receptor or P2RX7) - Discontinued Products P2X Purinoceptor 7 (P2Z Receptor or P2RX7) - Product Development Milestones Featured News & Press Releases Mar 03, 2017: Biosceptre publishes a clinical study of topical drug BIL010t as therapy for Basal cell carcinoma Dec 18, 2014: Alzheimer's Drug Discovery Foundation And Axxam Continue Their Successful Collaboration To Develop Novel Therapeutics For Alzheimer's Disease Jul 22, 2014: Biosceptre Announces Positive Phase I Results for BIL-010t to Treat Basal Cell Carcinoma Jan 25, 2012: Affectis Receives European Patent For AFC-5128 And Other P2X7 Antagonists Jun 29, 2009: Evotec Announces The Successful Completion Of The First Phase I Study With EVT 401 Oct 09, 2008: Evotec Announces Phase I Initiation With P2X7 Antagonist Appendix Methodology Coverage Secondary Research Primary Research Expert Panel Validation Contact Us Disclaimer
List of Tables
Number of Products under Development by Stage of Development, H2 2017 Number of Products under Development by Therapy Areas, H2 2017 Number of Products under Development by Indications, H2 2017 Number of Products under Development by Indications, H2 2017 (Contd..1), H2 2017 Number of Products under Development by Companies, H2 2017 Products under Development by Companies, H2 2017 Products under Development by Companies, H2 2017 (Contd..1), H2 2017 Number of Products by Stage and Mechanism of Actions, H2 2017 Number of Products by Stage and Route of Administration, H2 2017 Number of Products by Stage and Molecule Type, H2 2017 Pipeline by Affectis Pharmaceuticals AG, H2 2017 Pipeline by Axxam SpA, H2 2017 Pipeline by Biosceptre International Ltd, H2 2017 Pipeline by Evotec AG, H2 2017 Pipeline by Johnson & Johnson, H2 2017 Pipeline by Medestea Research & Production SpA, H2 2017 Dormant Projects, H2 2017 Discontinued Products, H2 2017



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