Next-Generation Sequencing (NGS) Services Market Size, Share & Trends Analysis Report By Service Type (Single Cell Seq, Small RNA Seq), By Workflow, By End Use, And Segment Forecasts, 2018 - 2025

Published: Nov, 2018 | Pages: 120 | Publisher: Grand View Research
Industry: Biotechnology | Report Format: Electronic (PDF)

The global next-generation sequencing (NGS) services market size is expected to reach USD 2.87 billion by 2025 at a 13.6% CAGR during the forecast period, according to a new report by Grand View Research, Inc. Development of NGS technologies has revolutionized gene sequencing in terms of reproducibility and cost savings.

This has resulted in introduction of several advancements in NGS technology to promote its usage in clinical labs and hospitals. Most current innovations in this field revolve around simplifying usage of seq-technology and making it more sophisticated. These factors have driven the uptake of NGS services across various end users.

Conventional disease testing service providers have broadened their portfolio with a rising trend of seq-based genetic tests. For example, in October 2014, ARUP Laboratories collaborated with the Children's Hospital of Philadelphia (CHOP). The service provision for NGS-based HLA genotyping, including HLA Class II and HLA Class I, began in November 2017.

With rising trend of high throughput sequencing within the pharma and biotech industry, there is a need for more developments to improve the speed and convenience of high throughput seq-platforms and simplify workflows. As a result, companies are focusing on development of solutions to simplify the amplification and purification of sample and starting input.

In July 2017, Norgen released the new Small RNA Library Prep Kit for Illumina. This kit is being developed to generate small RNA libraries and is optimized for samples with low input RNA (0.5-1ng), such as urine, serum, plasma, cerebral spinal fluid (CSF), blood, and exosomes.

Further key findings from the report suggest:

• Human genome sequencing services held the largest revenue share owing to greater penetration of whole genome and whole exome sequencing

• Gene regulation services, particularly small RNA sequencing and ChIP-seq, is anticipated to grow at a lucrative pace during the forecast period. Rising investment in RNA sequencing is driving the growth of gene regulation services

• Increase in installation of sequencing platforms is attributive to the larger revenue share of sequencing services as compared to other workflow steps. High maintenance and recovery costs of this step have also resulted in greater revenue generation

• Universities and other research entities have emerged as prominent end users owing to growing application of NGS technology for cancer prognosis as well as diagnosis and major projects taken up by academicians and universities

• North America dominated the market by revenue in 2017, owing to higher penetration of the technology in this region and availability of funds to employ the technique and derive research findings for disease targeting

• Various prominent players in this market include Illumina, Inc.; Eurofins Genomics; BGI; and GENEWIZ Germany GmbH. Companies such as GENEWIZ and Novogene Corporation are engaged in offering NGS services based on platforms from major NGS developers

• Companies such as Illumina and BGI, on the other hand, are involved in developing sequencing instruments and offering services to research entities.

 Table of Contents

Chapter 1 Executive Summary
                 1.1 Market Snapshot

Chapter 2 Research Methodology
                 2.1 Information Procurement
                     2.1.1 Purchased Database
                     2.1.2 GVR's Internal Database
                 2.2 Data Analysis
                 2.3 Market Formulation & Validation
                 2.4 Approaches for Market Estimation
                     2.4.1 Approach 1: Commodity Flow & Bottom Up Approach
                     2.4.2 Approach 2: Top Down and Parent Market Analysis

Chapter 3 Market Variables, Trends & Scope
                 3.1 Market Segmentation & Scope
                     3.1.1 Market driver analysis
                         3.1.1.1 Decline in sequencing prices
                         3.1.1.2 Growing awareness about women & reproductive health
                         3.1.1.3 Strategies undertaken for implementation of clinical NGS
                     3.1.2 Market restraint analysis
                         3.1.2.1 Issues pertaining to conducting large - scale NGS analysis workflows
                         3.1.2.2 Analytical challenges in single cell sequencing
                 3.2 Penetration & Growth Prospect Mapping For Service Type, 2017
                 3.3 Global Next-Generation Sequencing Services Market - Swot Analysis, By Factor (Political & Legal, Economic And Technological)
                 3.4 Industry Analysis - Porter's

Chapter 4 Global Next-Generation Sequencing Services Market Categorization: Service Type Estimates & Trend Analysis
                 4.1 Global Next-Generation Sequencing Services Market: Service Type Movement Analysis
                 4.2 Human Genome Sequencing Services
                     4.2.1 Global human genome sequencing services market, 2014 - 2025 (USD Million)
                 4.3 Single Cell Sequencing Services
                     4.3.1 Global single cell sequencing services market, 2014 - 2025 (USD Million)
                 4.4 Microbial Genome - based Sequencing Services
                     4.4.1 Global microbial genome - based sequencing services market, 2014 - 2025 (USD Million)
                 4.5 Gene Regulation Services
                     4.5.1 Global gene regulation services market, 2014 - 2025 (USD Million)
                     4.5.2 Small RNA sequencing service
                         4.5.2.1 Global small RNA sequencing services market, 2014 - 2025 (USD Million)
                     4.5.3 ChIP sequencing
                         4.5.3.1 Global ChIP sequencing services market, 2014 - 2025 (USD Million)
                     4.5.4 Other gene regulation - based service
                         4.5.4.1 Global other gene regulation - based service market, 2014 - 2025 (USD Million)
                 4.6 Animal & Plant Sequencing
                     4.6.1 Global animal & plant sequencing services market, 2014 - 2025 (USD Million)
                 4.7 Other Sequencing Services
                     4.7.1 Global other sequencing services market, 2014 - 2025 (USD Million)

Chapter 5 Global Next-Generation Sequencing Services Market Categorization: Workflow Estimates & Trend Analysis
                 5.1 Global Next-Generation Sequencing Services Market: Workflow Movement Analysis
                 5.2 Pre Sequencing Service
                     5.2.1 Global pre sequencing service market, 2014 - 2025 (USD Million)
                 5.3 Sequencing Service
                     5.3.1 Global sequencing service market, 2014 - 2025 (USD Million)
                 5.4 Data Analysis Service
                     5.4.1 Global data analysis service market, 2014 - 2025 (USD Million)

Chapter 6 Global Next-Generation Sequencing Services Market Categorization: End-use Estimates & Trend Analysis
                 6.1 Global Next-Generation Sequencing Services Market: End-use Movement Analysis
                 6.2 Universities & Other Research Entities
                     6.2.1 Global Next-Generation sequencing services market in universities & other research entities, 2014 - 2025 (USD Million)
                 6.3 Hospitals & Clinics
                     6.3.1 Global Next-Generation sequencing services market in hospitals & clinics, 2014 - 2025 (USD Million)
                 6.4 Pharma & Biotech Entities
                     6.4.1 Global Next-Generation sequencing services market in pharma & biotech entities, 2014 - 2025 (USD Million)
                 6.5 Other End-use
                     6.5.1 Global Next-Generation sequencing services market for other End-use, 2014 - 2025 (USD Million)

Chapter 7 Global Next-Generation Sequencing Services Market Categorization: Regional Estimates & Trend Analysis, by Service Type, Workflow, & End-use
                 7.1 Global Next-Generation Sequencing Services Market Share By Regional, 2017 & 2025
                 7.2 North America
                     7.2.1 North America Next-Generation sequencing services market, 2014 - 2025 (USD Million)
                     7.2.2 U.S.
                         7.2.2.1 U.S. Next-Generation sequencing services market, 2014 - 2025 (USD Million)
                     7.2.3. Canada
                         7.2.3.1 Canada Next-Generation sequencing services market, 2014 - 2025 (USD Million)
                 7.3 Europe
                     7.3.1 Europe Next-Generation sequencing services market, 2014 - 2025 (USD Million)
                     7.3.2 Germany
                         7.3.2.1 Germany Next-Generation sequencing services market, 2014 - 2025 (USD Million)
                     7.3.3 U.K.
                         7.3.3.1 U.K. Next-Generation sequencing services market, 2014 - 2025 (USD Million)
                 7.4 Asia Pacific
                     7.4.1 Asia Pacific Next-Generation sequencing services market, 2014 - 2025 (USD Million)
                     7.4.2 Japan
                         7.4.2.1 Japan Next-Generation sequencing services market, 2014 - 2025 (USD Million)
                     7.4.3 China
                         7.4.3.1 China Next-Generation sequencing services market, 2014 - 2025 (USD Million)
                 7.5 Latin America
                     7.5.1 Latin America Next-Generation sequencing services market, 2014 - 2025 (USD Million)
                     7.5.2 Brazil
                         7.5.2.1 Brazil Next-Generation sequencing services market, 2014 - 2025 (USD Million)
                 7.6 MEA
                     7.6.1 MEA Next-Generation sequencing services market, 2014 - 2025 (USD Million)
                     7.6.2 South Africa
                         7.6.2.1 South Africa Next-Generation sequencing services market, 2014 - 2025 (USD Million)

Chapter 8 Global Next-Generation Sequencing Services Market: Competitive Landscape
                 8.1 Strategy Framework
                 8.2 Company Profiles
                     8.2.1 Illumina, Inc.
                         8.2.1.1 Company Overview
                         8.2.1.2 Financial Performance
                         8.2.1.3 Product Benchmarking
                         8.2.1.4 Strategic Initiatives
                     8.2.2 Veritas Genetics
                         8.2.2.1 Company Overview
                         8.2.2.2 Financial Performance
                         8.2.2.3 Product Benchmarking
                         8.2.2.4 Strategic Initiatives
                     8.2.3 BGI
                         8.2.3.1 Company Overview
                         8.2.3.2 Financial Performance
                         8.2.3.3 Product Benchmarking
                         8.2.3.4 Strategic Initiatives
                     8.2.4 GENEWIZ Germany GmbH
                         8.2.4.1 Company Overview
                         8.2.4.2 Financial Performance
                         8.2.4.3 Product Benchmarking
                         8.2.4.4 Strategic Initiatives
                     8.2.5 abm Inc.
                         8.2.5.1 Company Overview
                         8.2.5.2 Financial Performance
                         8.2.5.3 Product Benchmarking
                         8.2.5.4 Strategic Initiatives
                     8.2.6 ARUP Laboratories
                         8.2.6.1 Company overview
                         8.2.6.2 Financial performance
                         8.2.6.3 Product benchmarking
                         8.2.6.4 Strategic Initiatives
                     8.2.7 Novogene Corporation
                         8.2.7.1 Company overview
                         8.2.7.2 Financial performance
                         8.2.7.3 Product benchmarking
                         8.2.7.4 Strategic Initiatives
                     8.2.8 Lucigen
                         8.2.8.1 Company overview
                         8.2.8.2 Financial performance
                         8.2.8.3 Product benchmarking
                         8.2.8.4 Strategic initiatives
                     8.2.9 Quest Diagnostics
                         8.2.9.1 Company overview
                         8.2.9.2 Financial performance
                         8.2.9.3 Product benchmarking
                         8.2.9.4 Strategic initiatives
                     8.2.10 Gene by Gene
                         8.2.10.1 Company overview
                         8.2.10.2 Financial performance
                         8.2.10.3 Product benchmarking
                         8.2.10.4 Strategic initiatives
                     8.2.11 NanoString Technologies, Inc.
                         8.2.11.1 Company overview
                         8.2.11.2 Financial performance
                         8.2.11.3 Product benchmarking
                         8.2.11.4 Strategic initiatives
                     8.2.12 Pacific Biosciences of California, Inc
                         8.2.12.1 Company overview
                         8.2.12.2 Financial performance
                         8.2.12.3 Product benchmarking
                         8.2.12.4 Strategic Initiatives

List of Tables

TABLE 1 North America next-generation sequencing services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 2 North America next-generation sequencing - based gene regulation services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 3 North America next-generation sequencing services market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 4 North America next-generation sequencing services market estimates & forecasts, by End-use, 2014 - 2025 (USD Million)
TABLE 5 U.S. next-generation sequencing services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 6 U.S. next-generation sequencing - based gene regulation services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 7 U.S. next-generation sequencing services market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 8 U.S. next-generation sequencing services market estimates & forecasts, by End-use, 2014 - 2025 (USD Million)
TABLE 9 Canada next-generation sequencing services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 10 Canada next-generation sequencing - based gene regulation services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 11 Canada next-generation sequencing services market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 12 Canada next-generation sequencing services market estimates & forecasts, by End-use, 2014 - 2025 (USD Million)
TABLE 13 Europe next-generation sequencing services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 14 Europe next-generation sequencing - based gene regulation services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 15 Europe next-generation sequencing services market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 16 Europe next-generation sequencing services market estimates & forecasts, by End-use, 2014 - 2025 (USD Million)
TABLE 17 Germany next-generation sequencing services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 18 Germany next-generation sequencing - based gene regulation services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 19 Germany next-generation sequencing services market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 20 Germany next-generation sequencing services market estimates & forecasts, by End-use, 2014 - 2025 (USD Million)
TABLE 21 U.K. next-generation sequencing services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 22 U.K. next-generation sequencing - based gene regulation services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 23 U.K. next-generation sequencing services market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 24 U.K. next-generation sequencing services market estimates & forecasts, by End-use, 2014 - 2025 (USD Million)
TABLE 25 Asia Pacific next-generation sequencing services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 26 Asia Pacific next-generation sequencing - based gene regulation services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 27 Asia Pacific next-generation sequencing services market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 28 Asia Pacific next-generation sequencing services market estimates & forecasts, by End-use, 2014 - 2025 (USD Million)
TABLE 29 Japan next-generation sequencing services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 30 Japan next-generation sequencing - based gene regulation services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 31 Japan next-generation sequencing services market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 32 Japan next-generation sequencing services market estimates & forecasts, by End-use, 2014 - 2025 (USD Million)
TABLE 33 China next-generation sequencing services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 34 China next-generation sequencing - based gene regulation services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 35 China next-generation sequencing services market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 36 China next-generation sequencing services market estimates & forecasts, by End-use, 2014 - 2025 (USD Million)
TABLE 37 Latin America next-generation sequencing services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 38 Latin America next-generation sequencing - based gene regulation services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 39 Latin America next-generation sequencing services market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 40 Latin America next-generation sequencing services market estimates & forecasts, by End-use, 2014 - 2025 (USD Million)
TABLE 41 Brazil next-generation sequencing services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 42 Brazil next-generation sequencing - based gene regulation services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 43 Brazil next-generation sequencing services market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 44 Brazil next-generation sequencing services market estimates & forecasts, by End-use, 2014 - 2025 (USD Million)
TABLE 45 MEA next-generation sequencing services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 46 MEA next-generation sequencing - based gene regulation services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 47 MEA next-generation sequencing services market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 48 MEA next-generation sequencing services market estimates & forecasts, by End-use, 2014 - 2025 (USD Million)
TABLE 49 South Africa next-generation sequencing services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 50 South Africa next-generation sequencing - based gene regulation services market estimates & forecasts, by service type, 2014 - 2025 (USD Million)
TABLE 51 South Africa next-generation sequencing services market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 52 South Africa next-generation sequencing services market estimates & forecasts, by End-use, 2014 - 2025 (USD Million)

List of Figures

FIG. 1 Market summary
FIG. 2 Market research process
FIG. 3 Information procurement
FIG. 4 Primary research pattern
FIG. 5 Market research approaches
FIG. 6 Value chain based sizing & forecasting
FIG. 7 QFD modelling for market share assessment
FIG. 8 Market trends & outlook
FIG. 9 Market segmentation & scope
FIG. 10 Market driver relevance analysis (Current & future impact)
FIG. 11 Market restraint relevance analysis (Current & future impact)
FIG. 12 Penetration & growth prospect mapping for service type, 2017
FIG. 13 SWOT Analysis, By Factor (political & legal, economic and technological)
FIG. 14 Porter's Five Forces Analysis
FIG. 15 Global next-generation sequencing services market: Service type outlook key takeaways
FIG. 16 Global next-generation sequencing services market: Use - type movement analysis
FIG. 17 Global human genome sequencing services market, 2014 - 2025 (USD Million)
FIG. 18 Global single cell sequencing services market, 2014 - 2025 (USD Million)
FIG. 19 Global microbial genome - based sequencing services market, 2014 - 2025 (USD Million)
FIG. 20 Global human genome sequencing services market, 2014 - 2025 (USD Million)
FIG. 21 Global small RNA sequencing services market, 2014 - 2025 (USD Million)
FIG. 22 Global ChIP sequencing services market, 2014 - 2025 (USD Million)
FIG. 23 Global other gene regulation - based services market, 2014 - 2025 (USD Million)
FIG. 24 Global animal & plant sequencing services market, 2014 - 2025 (USD Million)
FIG. 25 Global human genome sequencing services market, 2014 - 2025 (USD Million)
FIG. 26 Global next-generation sequencing services market: Workflow outlook key takeaways
FIG. 27 Global next-generation sequencing services market: Workflow movement analysis
FIG. 28 Global pre sequencing service market, 2014 - 2025 (USD Million)
FIG. 29 Global sequencing service market, 2014 - 2025 (USD Million)
FIG. 30 Global data analysis service market, 2014 - 2025 (USD Million)
FIG. 31 Global next-generation sequencing services market: End-use outlook key takeaways
FIG. 32 Global next-generation sequencing services market: End-use movement analysis
FIG. 33 Global next-generation sequencing services market in universities & other research entities, 2014 - 2025 (USD Million)
FIG. 34 Global next-generation sequencing services market in hospitals & clinics, 2014 - 2025 (USD Million)
FIG. 35 Global next-generation sequencing services market in pharma & biotech entities, 2014 - 2025 (USD Million)
FIG. 36 Global next-generation sequencing services market for other End-use, 2014 - 2025 (USD Million)
FIG. 37 Regional market place: Key takeaway
FIG. 38 Global next-generation sequencing services market: Regional outlook, 2017 & 2025
FIG. 39 North America next-generation sequencing services market, 2014 - 2025 (USD Million)
FIG. 40 U.S. next-generation sequencing services market, 2014 - 2025 (USD Million)
FIG. 41 Canada next-generation sequencing services market, 2014 - 2025 (USD Million)
FIG. 42 Europe next-generation sequencing services market, 2014 - 2025 (USD Million)
FIG. 43 Germany next-generation sequencing services market, 2014 - 2025 (USD Million)
FIG. 44 U.K. next-generation sequencing services market, 2014 - 2025 (USD Million)
FIG. 45 Asia Pacific next-generation sequencing services market, 2014 - 2025 (USD Million)
FIG. 46 Japan next-generation sequencing services market, 2014 - 2025 (USD Million)
FIG. 47 China next-generation sequencing services market, 2014 - 2025 (USD Million)
FIG. 48 Latin America next-generation sequencing services market, 2014 - 2025 (USD Million)
FIG. 49 Brazil next-generation sequencing services market, 2014 - 2025 (USD Million)
FIG. 50 MEA next-generation sequencing services market, 2014 - 2025 (USD Million)
FIG. 51 South Africa next-generation sequencing services market, 2014 - 2025 (USD Million)
FIG. 52 List of companies
FIG. 53 Strategy Framework
FIG. 54 Participant categorization

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