Long Read Sequencing Market Size, Share & Trends Analysis Report By Workflow, By Technology (SMRT Sequencing), By Product, By Application, By End Use (Academic & Clinical Research), And Segment Forecasts, 2019 - 2025

Published: Sep, 2019 | Pages: 150 | Publisher: Grand View Research
Industry: Biotechnology | Report Format: Electronic (PDF)

The global long read sequencing market size is expected to reach USD 3.4 billion by 2025, according to a new report by Grand View Research, Inc., registering a 23.5% CAGR over the forecast period. Rapid advancements in third-generation long-read sequence analysis techniques are expected to bring a new era of research in the field of medical and biological sciences.

In addition, advantages offered by single-molecule real-time sequencing (SMRT) and Nanopore platforms over second-generation technologies are anticipated to enhance the adoption of these protocols. For instance, long reads generated by SMRT sequencers span across possible repetitive regions and provide a comprehensive view of the whole genome. Therefore, these technologies are adopted in the identification of genetic and structural variants.

Owing to the advantages offered by long-read technology, manufacturers are increasingly enhancing their product offerings to overcome technical as well as data analysis limitations. For instance, in January 2019, Oxford Nanopore Technologies launched NanoPipe, a web server for data analysis of nanopore MinION. The software is designed such that it can be easily used by wet-lab biologists with little knowledge about bioinformatics platforms as well as experienced bioinformaticians.

Further key findings from the report suggest:

• The SMRT segment accounted for a major share by technology in 2018 and is projected to maintain its dominance throughout the forecast period. Factors such as longer reads, high accuracy, and modified base detection make SMRT a method of choice for complete genome analysis

• Nanopore technology is anticipated to witness lucrative growth owing to the portable nature of commercially available Nanopore sequencers. This property of Nanopore sequencers makes them useful in generation of immediate, real-time data during viral outbreaks in remote areas

• On the basis of product, consumables formed the largest revenue generating segment in 2018 and is estimated to remain so throughout the forecast period owing to high utilization of consumables in every step across the workflow

• By application, identification & fine mapping of structural variation occupied a major share in 2018 as long reads allow efficient distinction of haplotypes and enhance the accuracy of analysis of structural variations

• Based on workflow, the data analysis segment is expected to expand at a lucrative CAGR owing to efforts taken by several product manufacturers to enhance adoption of data analysis software

• Academic research accounted for the largest share by end use as a result of higher usage of these methodologies in research, academic workshops, and on-site bioinformatics courses offered by universities

• Asia Pacific is expected to expand at the fastest growth rate throughout the forecast period. Lucrative opportunities offered by emerging nations has attracted investments from global firms in the region

• Pacific Biosciences of California, Inc. and Oxford Nanopore Technologies Limited are some of the prominent participants operating in this market. These participants are engaged in new product development and strategic alliances to maintain market share.

 Table of Contents

Chapter 1 Executive Summary
                   1.1 Market Snapshot
Chapter 2 Research Methodology
                   2.1 Information Procurement
                       2.1.1 Purchased database
                       2.1.2 GVR's internal database
                       2.1.3 Secondary sources
                       2.1.4 Primary research
                       2.1.5 Details of primary research
                   2.2 Information or Data Analysis
                       2.2.1 Data analysis models
                   2.3 Market Formulation & Validation
                   2.4 Model Details
                       2.4.1 Commodity flow analysis (Model 1)
                           2.4.1.1 Approach 1: Commodity flow approach
                   2.5 List of Secondary Sources
                   2.6 List of Primary Sources
                   2.7 Objectives
                       2.7.1 Objective 1
                       2.7.2 Objective 2
Chapter 3 Market Variables, Trends, & Scope
                   3.1 Market Segmentation & Scope
                       3.1.1 Market driver analysis
                           3.1.1.1 Advantages of long read sequencing
                           3.1.1.2 Potential applications in clinical sequencing and analysis
                           3.1.1.3 Advancements in data analysis
                       3.1.2 Market restraint analysis
                           3.1.2.1 High cost
                           3.1.2.2 Technological challenges
                   3.2 Penetration & Growth Prospect Mapping for Applications, 2018
                   3.3 Long Read Sequencing - SWOT Analysis, By Factor (Political & Legal, Economic, And Technological)
                   3.4 Industry Analysis - Porter's
Chapter 4 Long Read Sequencing Market: Technology Estimates & Trend Analysis
                   4.1 Long Read Sequencing Market: Technology Movement Analysis, 2018 & 2025
                   4.2 Single-Molecule Real-Time Sequencing (SMRT)
                       4.2.1 Global SMRT sequencing market, 2014 - 2025 (USD Million)
                   4.3 Nanopore Sequencing
                       4.3.1 Global nanoporer sequencing market, 2014 - 2025 (USD Million)
Chapter 5 Long Read Sequencing Market: Product Estimates & Trend Analysis
                   5.1 Long Read Sequencing Market: Product Movement Analysis, 2018 & 2025
                   5.2 Instruments
                       5.2.1 Long read sequencing instruments market, 2014 - 2025 (USD Million)
                   5.3 Consumables
                       5.3.1 Long read sequencing market for consumables, 2014 - 2025 (USD Million)
                   5.4 Services
                       5.4.1 Long read sequencing services market, 2014 - 2025 (USD Million)
Chapter 6 Long Read Sequencing Market: Application Estimates & Trend Analysis
                   6.1 Long Read Sequencing Market: Application Movement Analysis, 2018 & 2025
                   6.2 Identification & Fine Mapping Of Structural Variation
                       6.2.1 Long read sequencing market for identification & fine mapping of structural variation, 2014 - 2025 (USD Million)
                   6.3 Tandem Repeat Sequencing
                       6.3.1 Long read sequencing market for tandem repeat sequencing, 2014 - 2025 (USD Million)
                   6.4 Pseudogene Discrimination
                       6.4.1 Long read sequencing market for pseudogene discrimination , 2014 - 2025 (USD Million)
                   6.5 Resolving Allele Phasing
                       6.5.1 Long read sequencing market for resolving allele phasing, 2014 - 2025 (USD Million)
                   6.6 Reproductive Genomics
                       6.6.1 Long read sequencing market for reproductive genomics , 2014 - 2025 (USD Million)
                   6.7 Cancer
                       6.7.1 Long read sequencing market for cancer , 2014 - 2025 (USD Million)
                   6.8 Viral & Microbial Sequencing
                       6.8.1 Long read sequencing market for viral & microbial sequencing, 2014 - 2025 (USD Million)
                   6.9 Others
                       6.9.1 Long read sequencing market for other applications, 2014 - 2025 (USD Million)
Chapter 7 Long Read Sequencing Market: Workflow Estimates & Trend Analysis
                   7.1 Long Read Sequencing Market: Workflow Movement Analysis, 2018 & 2025
                   7.2 Pre-Sequencing
                       7.2.1 Long read sequencing market for pre-sequencing, 2014 - 2025 (USD Million)
                   7.3 Sequencing
                       7.3.1 Long read sequencing market for sequencing, 2014 - 2025 (USD Million)
                   7.4 Data Analysis
                       7.4.1 Long read sequencing market for data analysis, 2014 - 2025 (USD Million)
Chapter 8 Long Read Sequencing Market: End Use Estimates & Trend Analysis
                   8.1 Long Read Sequencing Market: End Use Movement Analysis, 2018 & 2025
                   8.2 Academic Research
                       8.2.1 Long read sequencing market for academic research, 2014 - 2025 (USD Million)
                   8.3 Clinical Research
                       8.3.1 Long read sequencing market for clinical research, 2014 - 2025 (USD Million)
                   8.4 Hospitals & Clinics
                       8.4.1 Long read sequencing market for hospitals & clinics, 2014 - 2025 (USD Million)
                   8.5 Pharma & Biotech Entities
                       8.5.1 Long read sequencing market for pharma & biotech entities, 2014 - 2025 (USD Million)
                   8.6 Other End Users
                       8.6.1 Long read sequencing market for other end users, 2014 - 2025 (USD Million)
Chapter 9 Long Read Sequencing Market: Regional Estimates & Trend Analysis, by Technology, Product, Application, Workflow, and End Use
                   9.1 Long Read Sequencing Market Share By Region, 2018 & 2025
                   9.2 North America
                       9.2.1 North America long read sequencing market, 2014 - 2025 (USD Million)
                       9.2.2 U.S.
                           9.2.2.1 U.S. long read sequencing market, 2014 - 2025 (USD Million)
                       9.2.3 Canada
                           9.2.3.1 Canada long read sequencing market, 2014 - 2025 (USD Million)
                   9.3 Europe
                       9.3.1 Europe long read sequencing market, 2014 - 2025 (USD Million)
                       9.3.2 Germany
                           9.3.2.1 Germany long read sequencing market, 2014 - 2025 (USD Million)
                       9.3.3 U.K.
                           9.3.3.1 U.K. long read sequencing market, 2014 - 2025 (USD Million)
                   9.4 Asia Pacific
                       9.4.1 Asia Pacific long read sequencing market, 2014 - 2025 (USD Million)
                       9.4.2 Japan
                           9.4.2.1 Japan long read sequencing market, 2014 - 2025 (USD Million)
                       9.4.3 China
                           9.4.3.1 China long read sequencing market, 2014 - 2025 (USD Million)
                   9.5 Latin America
                       9.5.1 Latin America long read sequencing market, 2014 - 2025 (USD Million)
                       9.5.2 Brazil
                           9.5.2.1 Brazil long read sequencing market, 2014 - 2025 (USD Million)
                   9.6 Middle East & Africa (MEA)
                       9.6.1 MEA long read sequencing market, 2014 - 2025 (USD Million)
                       9.6.2 South Africa
                           9.6.2.1 South Africa long read sequencing market, 2014 - 2025 (USD Million)
Chapter 10 Competitive Landscape
                   10.1 Strategy Framework
                   10.2 Market Participation Categorization
                   10.3 Company Profiles
                   10.4 Pacific Biosciences of California, Inc.
                       10.4.1 Company overview
                       10.4.2 Financial performance
                       10.4.3 Product benchmarking
                       10.4.4 Strategic initiatives
                   10.5 Oxford Nanopore Technologies Limited
                       10.5.1 Company overview
                       10.5.2 Financial performance
                       10.5.3 Product benchmarking
                       10.5.4 Strategic initiatives
                   10.6 Quantapore, Inc.
                       10.6.1 Company overview
                       10.6.2 Financial performance
                       10.6.3 Product benchmarking
                       10.6.4 Strategic initiatives
                   10.7 Stratos Genomics Inc.
                       10.7.1 Company overview
                       10.7.2 Financial performance
                       10.7.3 Product benchmarking
                       10.7.4 Strategic initiatives
                   10.8 MicrobesNG
                       10.8.1 Company overview
                       10.8.2 Financial performance
                       10.8.3 Product benchmarking
                       10.8.4 Strategic initiatives
                   10.9 Institute of Integrative Biology of the Cell (I2BC)
                       10.9.1 Company overview
                       10.9.2 Financial performance
                       10.9.3 Product benchmarking
                       10.9.4 Strategic initiatives
                   10.10 BaseClear B.V.
                       10.10.1 Company overview
                       10.10.2 Financial performance
                       10.10.3 Product benchmarking
                       10.10.4 Strategic initiatives
                   10.11 Future Genomics Technologies B.V.
                       10.11.1 Company overview
                       10.11.2 Financial performance
                       10.11.3 Product benchmarking
                       10.11.4 Strategic initiatives
                   10.12 Garvan Institute of Medical Research
                       10.12.1 Company overview
                       10.12.2 Financial performance
                       10.12.3 Product benchmarking
                       10.12.4 Strategic initiatives
                   10.13 Genome Transcriptome Facility of Bordeaux
                       10.13.1 Company overview
                       10.13.2 Financial performance
                       10.13.3 Product benchmarking
                       10.13.4 Strategic initiatives
                   10.14 NextOmics
                       10.14.1 Company overview
                       10.14.2 Financial performance
                       10.14.3 Product benchmarking
                       10.14.4 Strategic initiatives
                   10.15 Takara Bio Inc.
                       10.15.1 Company overview
                       10.15.2 Financial performance
                       10.15.3 Product benchmarking
                       10.15.4 Strategic initiatives

List of Tables

TABLE 1 List of secondary sources
TABLE 2 North America long read sequencing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 3 North America long read sequencing market estimates & forecasts, by product, 2014 - 2025 (USD Million)
TABLE 4 North America long read sequencing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 5 North America long read sequencing market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 5 North America long read sequencing market estimates & forecasts, by end use, 2014 - 2025 (USD Million)
TABLE 6 U.S. long read sequencing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 7 U.S. long read sequencing market estimates & forecasts, by product, 2014 - 2025 (USD Million)
TABLE 8 U.S. long read sequencing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 9 U.S. long read sequencing market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 10 U.S. long read sequencing market estimates & forecasts, by end use, 2014 - 2025 (USD Million)
TABLE 11 Canada long read sequencing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 12 Canada long read sequencing market estimates & forecasts, by product, 2014 - 2025 (USD Million)
TABLE 13 Canada long read sequencing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 14 Canada long read sequencing market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 15 Canada long read sequencing market estimates & forecasts, by end use, 2014 - 2025 (USD Million)
TABLE 16 Europe long read sequencing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 17 Europe long read sequencing market estimates & forecasts, by product, 2014 - 2025 (USD Million)
TABLE 18 Europe long read sequencing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 19 Europe long read sequencing market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 20 Europe long read sequencing market estimates & forecasts, by end use, 2014 - 2025 (USD Million)
TABLE 21 Germany long read sequencing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 22 Germany long read sequencing market estimates & forecasts, by product, 2014 - 2025 (USD Million)
TABLE 23 Germany long read sequencing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 24 Germany long read sequencing market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 25 Germany long read sequencing market estimates & forecasts, by end use, 2014 - 2025 (USD Million)
TABLE 26 U.K. long read sequencing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 27 U.K. long read sequencing market estimates & forecasts, by product, 2014 - 2025 (USD Million)
TABLE 28 U.K. long read sequencing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 29 U.K. long read sequencing market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 30 U.K. long read sequencing market estimates & forecasts, by end use, 2014 - 2025 (USD Million)
TABLE 31 Asia Pacific long read sequencing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 32 Asia Pacific long read sequencing market estimates & forecasts, by product, 2014 - 2025 (USD Million)
TABLE 33 Asia Pacific long read sequencing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 34 Asia Pacific long read sequencing market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 35 Asia Pacific long read sequencing market estimates & forecasts, by end use, 2014 - 2025 (USD Million)
TABLE 36 Japan long read sequencing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 37 Japan long read sequencing market estimates & forecasts, by product, 2014 - 2025 (USD Million)
TABLE 38 Japan long read sequencing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 39 Japan long read sequencing market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 40 Japan long read sequencing market estimates & forecasts, by end use, 2014 - 2025 (USD Million)
TABLE 41 China long read sequencing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 42 China long read sequencing market estimates & forecasts, by product, 2014 - 2025 (USD Million)
TABLE 43 China long read sequencing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 44 China long read sequencing market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 45 China long read sequencing market estimates & forecasts, by end use, 2014 - 2025 (USD Million)
TABLE 46 Latin America long read sequencing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 47 Latin America long read sequencing market estimates & forecasts, by product, 2014 - 2025 (USD Million)
TABLE 48 Latin America long read sequencing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 49 Latin America long read sequencing market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 50 Latin America long read sequencing market estimates & forecasts, by end use, 2014 - 2025 (USD Million)
TABLE 51 Brazil long read sequencing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 52 Brazil long read sequencing market estimates & forecasts, by product, 2014 - 2025 (USD Million)
TABLE 53 Brazil long read sequencing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 54 Brazil long read sequencing market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 55 Brazil long read sequencing market estimates & forecasts, by end use, 2014 - 2025 (USD Million)
TABLE 56 MEA long read sequencing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 57 MEA long read sequencing market estimates & forecasts, by product, 2014 - 2025 (USD Million)
TABLE 58 MEA long read sequencing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 59 MEA long read sequencing market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 60 MEA long read sequencing market estimates & forecasts, by end use, 2014 - 2025 (USD Million)
TABLE 61 South Africa long read sequencing market estimates & forecasts, by technology, 2014 - 2025 (USD Million)
TABLE 62 South Africa long read sequencing market estimates & forecasts, by product, 2014 - 2025 (USD Million)
TABLE 63 South Africa long read sequencing market estimates & forecasts, by application, 2014 - 2025 (USD Million)
TABLE 64 South Africa long read sequencing market estimates & forecasts, by workflow, 2014 - 2025 (USD Million)
TABLE 65 South Africa long read sequencing market estimates & forecasts, by end use, 2014 - 2025 (USD Million)

List of Figures

FIG. 1 Market snapshot
FIG. 2 Market research process
FIG. 3 Data triangulation techniques
FIG. 4 Primary research pattern
FIG. 5 Market research approaches
FIG. 6 Value chain based sizing & forecasting
FIG. 7 QFD modelling for market share assessment
FIG. 8 Market formulation & validation
FIG. 9 Market trends & outlook
FIG. 10 Market segmentation & scope
FIG. 11 Market driver relevance analysis (Current & future impact)
FIG. 12 Market restraint relevance analysis (Current & future impact)
FIG. 13 Penetration & growth prospect mapping for applications, 2018
FIG. 14 SWOT analysis, by factor (Political & legal, economic, and technological)
FIG. 15 Porter's Five Forces Analysis
FIG. 16 Long read sequencing market: Technology outlook key takeaways
FIG. 17 Long read sequencing market: Technology movement analysis
FIG. 18 Long read SMRT market, 2014 - 2025 (USD Million)
FIG. 19 Long read nanopore sequencing market, 2014 - 2025 (USD Million)
FIG. 20 Long read sequencing market: Product outlook key takeaways
FIG. 21 Long read sequencing market: Product movement analysis
FIG. 22 Long read sequencing instruments market, 2014 - 2025 (USD Million)
FIG. 23 Long read sequencing market for consumables, 2014 - 2025 (USD Million)
FIG. 24 Long read sequencing services market, 2014 - 2025 (USD Million)
FIG. 25 Long read sequencing market: Application outlook key takeaways
FIG. 26 Long read sequencing market: Application movement analysis
FIG. 27 Long read sequencing market for identification & fine mapping of structural variation, 2014 - 2025 (USD Million)
FIG. 28 Long read sequencing market for tandem repeat sequencing, 2014 - 2025 (USD Million)
FIG. 29 Long read sequencing market for pseudogene discrimination , 2014 - 2025 (USD Million)
FIG. 30 Long read sequencing market for resolving allele phasing, 2014 - 2025 (USD Million)
FIG. 31 Long read sequencing market for reproductive genomics, 2014 - 2025 (USD Million)
FIG. 32 Long read sequencing market for cancer, 2014 - 2025 (USD Million)
FIG. 33 Long read sequencing market for viral & microbial sequencing, 2014 - 2025 (USD Million)
FIG. 34 Long read sequencing market for other applications, 2014 - 2025 (USD Million)
FIG. 35 Long read sequencing market: Workflow outlook key takeaways
FIG. 36 Long read sequencing Market: Workflow Movement Analysis
FIG. 37 Long read sequencing market for pre-sequencing, 2014 - 2025 (USD Million)
FIG. 38 Long read sequencing market for sequencing, 2014 - 2025 (USD Million)
FIG. 39 Long read sequencing market for data analysis, 2014 - 2025 (USD Million)
FIG. 40 Long read sequencing market: End use outlook key takeaways
FIG. 41 Long read sequencing Market: End Use Movement Analysis
FIG. 42 Long read sequencing market for academic research, 2014 - 2025 (USD Million)
FIG. 43 Long read sequencing market for clinical research, 2014 - 2025 (USD Million)
FIG. 44 Long read sequencing market for hospitals & clinics, 2014 - 2025 (USD Million)
FIG. 45 Long read sequencing market for pharma & biotech entities, 2014 - 2025 (USD Million)
FIG. 46 Long read sequencing market for other end users, 2014 - 2025 (USD Million)
FIG. 47 Regional market place: Key takeaway
FIG. 48 Long read sequencing regional outlook, 2018 & 2025
FIG. 49 North America long read sequencing market, 2014 - 2025 (USD Million)
FIG. 50 U.S. long read sequencing market, 2014 - 2025 (USD Million)
FIG. 51 Canada long read sequencing market, 2014 - 2025 (USD Million)
FIG. 52 Europe long read sequencing market, 2014 - 2025 (USD Million)
FIG. 53 Germany long read sequencing market, 2014 - 2025 (USD Million)
FIG. 54 U.K. long read sequencing market, 2014 - 2025 (USD Million)
FIG. 55 Asia Pacific long read sequencing market, 2014 - 2025 (USD Million)
FIG. 56 Japan long read sequencing market, 2014 - 2025 (USD Million)
FIG. 57 China long read sequencing market, 2014 - 2025 (USD Million)
FIG. 58 Latin America long read sequencing market, 2014 - 2025 (USD Million)
FIG. 59 Brazil long read sequencing market, 2014 - 2025 (USD Million)
FIG. 60 MEA long read sequencing market, 2014 - 2025 (USD Million)
FIG. 61 South Africa long read sequencing market, 2014 - 2025 (USD Million)
FIG. 62 Strategy framework
FIG. 63 Participant categorization

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