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Published: Jul, 2019 | Pages:
135 | Publisher: Grand View Research
Industry: Biotechnology | Report Format: Electronic (PDF)
The global G-protein coupled receptors market size is expected to reach USD 4.36 billion by 2026 registering a CAGR of 6.7%, according to a new report by Grand View Research, Inc. Rising adoption of faster and accurate High-Throughput Screening (HTS) technology by pharmaceutical firms to develop potential G-protein coupled receptor-targeted therapeutics is expected to augment the market growth. HTS is used on the G-protein coupled receptor cell-based assays to assist several drug development programs. Structural and functional features of G-protein coupled receptors (GPCRs) allow it to mediate physiological responses to hormones, stimulants, and neurotransmitters, thus making them as potential therapeutic targets for various diseases. Recent advancements in the structural biology of GPCRs have provided insights into the molecular mechanisms of these receptors' activation and activity. Several pharmaceutical companies are undertaking efforts to develop G-protein coupled receptors-targeted therapeutics for several disorders. In December 2018, Boehringer Ingelheim collaborated with Domain Therapeutics to discover GPCR targets for the treatment of cancer, Central Nervous System (CNS), and immunological disorders. Moreover, in May 2019, Evotec OAI AG partnered with Euroscreen S.A. to improve its capabilities for GPCR targeting. Evotec OAI will access GPCR reagents and AequoScreenTM technology of Euroscreen for its drug discovery procedures. Such initiatives enhance the product adoption as well as drug screening expertise in the pharmaceutical industry. North America is likely to be at the forefront of the market throughout the forecast period due to heavy investments in cancer research to address the rising demand for drug discovery and development procedures in U.S. Whereas, Asia Pacific is expected to register the fastest CAGR over the forecast years. The region witnesses a rising number of therapeutics development and contract research, thus boosting G-protein coupled receptors market growth. Further key findings from the study suggest: • Easy availability of cell lines products and a large number of companies offering a variety of cell lines resulted in the largest revenue share of cell lines in 2018 • Increasing usage of fully equipped detection kits instead of cell lines, reagents, and ligands separately, marks the potential growth of detection kits in the near future • cAMP assays serve as a versatile platform in HTS for explaining the GPCR functions, which results in maximum revenue generation from these type of assays • Cancer research application accounted for the largest revenue share in 2018 owing to increased number of cancer cases and investments in oncology R&D • Ongoing research studies to evaluate the pharmacology of GPCRs in chronic inflammatory disorders reveals immense opportunities for research in inflammatory applications • Key companies in the G-protein coupled receptor market include Perkin Elmer, Inc.; Thermo Fisher Scientific; Eurofins Scientific; QIAGEN; Promega Corporation; and Merck KGaA • Acquisition, partnerships, and collaborations are the major strategies adopted by these companies to offer new GPCR-targeted medicines, thereby strengthening their presence in the global GPCRs market
Table of Contents
Chapter 1 Executive Summary
1.1 Market Outlook
1.2 Segment Outlook, 2015 - 2026
1.3 Competitive Insights, 2015 - 2026
Chapter 2 Research Methodology
2.1 Information Procurement
2.2 Information or Data Analysis
2.3 Market Formulation & Validation
Chapter 3 G-Protein Coupled Receptors (GPCR) Market Variables, Trends & Scope
3.1 G-Protein Coupled Receptors (GPCR) Market Outlook
3.2 Penetration & Growth Prospect Mapping for Assay Type, 2018
3.3 Technology Overview
3.3.1 Technology timeline
3.4 Regulatory Framework
3.4.1 Standards & compliances
3.5 G-Protein Coupled Receptors (GPCR) Market - Market Dynamics
3.5.1 Market driver analysis
3.5.1.1 Growing demand for GPCR assays in drug discovery studies
3.5.1.2 Rising number of initiatives by government and key players
3.5.1.3 Wide application of GPCRs in the treatment for various medical conditions
3.5.1.4 Increasing prevalence of chronic lifestyle disorders
3.5.2 Market restraint analysis
3.5.2.1 The complexity of the GPCR signalling system
3.5.3 Market Challenges analysis
3.5.3.1 Challenges with the purification of GPCRs
3.6 Business Environment Analysis: G-Protein Coupled Receptors (GPCR) Market
3.6.1 Industry analysis - Porter's
3.6.1.1 Supplier power
3.6.1.2 Buyer power
3.6.1.3 Substitution threat
3.6.1.4 Threat from new entrant
3.6.1.5 Competitive rivalry
3.6.2 G-protein coupled receptor (GPCr) Market-SWOT analysis, by factor (political & legal, economic and technological)
3.6.2.1 Major deals & strategic alliances analysis
3.6.2.2 Mergers & acquisitions
3.6.2.3 Product development
3.6.2.4 Partnerships and collaborations
3.6.3 Market entry strategies
Chapter 4 Market Categorization: Product Estimates & Trend Analysis
4.1 G-Protein Coupled Receptors (GPCR) Market: Product Movement Analysis & Market Share, 2018 & 2026
4.2 Cell Lines
4.2.1 Global GPCR cell lines market, 2015 - 2026 (USD Million)
4.3 Detection Kits
4.3.1 Global GPCR detection kits market, 2015 - 2026 (USD Million)
4.4 Cell Culture Reagents
4.4.1 Global GPCR cell culture reagents market, 2015 - 2026 (USD Million)
4.5 Ligands
4.5.1 Global GPCR ligands market, 2015 - 2026 (USD Million)
Chapter 5 Market Categorization: Assay Type Estimates & Trend Analysis
5.1 G-Protein Coupled Receptors (GPCR) Market: Assay Type Movement Analysis & Market Share, 2018 & 2026
5.2 cAMP Functional Assays
5.2.1 Global cAMP functional assays market, 2015 - 2026 (USD Million)
5.3 Calcium Functional Assays
5.3.1 Global calcium functional assays market, 2015 - 2026 (USD Million)
5.4 ?-Arrestin Functional Assays
5.4.1 Global ?-arrestin functional assays market, 2015 - 2026 (USD Million)
5.5 Radioligand Binding and GTP?S Functional Assays
5.5.1 Global radioligand binding and GTP?S functional assays market, 2015 - 2026 (USD Million)
5.6 Internalization Assays
5.6.1 Global internalization assays market, 2015 - 2026 (USD Million)
5.7 Trafficking Assays
5.7.1 Global trafficking assays market, 2015 - 2026 (USD Million)
5.8 Other Assays
5.8.1 Global other GPCR assays market, 2015 - 2026 (USD Million)
Chapter 6 Market Categorization: Application Estimates & Trend Analysis
6.1 G-Protein Coupled Receptors (GPCR) Market: Application Movement Analysis & Market Share, 2018 & 2026
6.2 Cancer Research
6.2.1 Global GPCR assays market for cancer research, 2015 - 2026 (USD Million)
6.3 Central Nervous System (CNS) Research
6.3.1 Global GPCR assays market for central nervous system (CNS) research, 2015 - 2026 (USD Million)
6.4 Metabolic Research
6.4.1 Global GPCR assays market for metabolic research, 2015 - 2026 (USD Million)
6.5 Cardiovascular Research
6.5.1 Global GPCR assays market for cardiovascular research, 2015 - 2026 (USD Million)
6.6 Respiratory Research
6.6.1 Global GPCR assays market for respiratory research, 2015 - 2026 (USD Million)
6.7 Inflammation Research
6.7.1 Global trafficking assays market, 2015 - 2026 (USD Million)
6.8 Other Application
6.8.1 Global GPCR assays market for other applications market, 2015 - 2026 (USD Million)
Chapter 7 Market Categorization: Regional Estimates & Trend Analysis, by Product, Assay Type & Application
7.1 Regional Market Snapshot
7.2 G-Protein Coupled Receptors (GPCR) Market Share by Region, 2018 & 2026
7.3 North America
7.3.1 North america G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million)
7.3.2 U.S.
7.3.2.1 U.S. G-protein coupled receptors (GPCR) market, by product, 2015 - 2026 (USD Million)
7.3.2.2 U.S. G-protein coupled receptors (GPCR) market, by assay type, 2015 - 2026 (USD Million)
7.3.2.3 U.S. G-protein coupled receptors (GPCR) market, by application, 2015 - 2026 (USD Million)
7.3.3 Canada
7.3.3.1 Canada G-protein coupled receptors (GPCR) market, by product, 2015 - 2026 (USD Million)
7.3.3.2 Canada G-protein coupled receptors (GPCR) market, by assay type, 2015 - 2026 (USD Million)
7.3.3.3 Canada G-protein coupled receptors (GPCR) market, by application, 2015 - 2026 (USD Million)
7.4 Europe
7.4.1 Europe G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million)
7.4.2 Germany
7.4.2.1 Germany G-protein coupled receptors (GPCR) market,by product, 2015 - 2026 (USD Million)
7.4.2.2 Germany G-protein coupled receptors (GPCR) market, by assay type, 2015 - 2026 (USD Million)
7.4.2.3 Germany G-protein coupled receptors (GPCR) market, by application, 2015 - 2026 (USD Million)
7.4.3 U.K.
7.4.3.1 U.K. G-protein coupled receptors (GPCR) market, by product, 2015 - 2026 (USD Million)
7.4.3.2 U.K. G-protein coupled receptors (GPCR) market, by assay type, 2015 - 2026 (USD Million)
7.4.3.3 U.K. G-protein coupled receptors (GPCR) market, by application, 2015 - 2026 (USD Million)
7.5 Asia Pacific
7.5.1 Asia Pacific G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million)
7.5.2 China
7.5.2.1 China G-protein coupled receptors (GPCR) market, by product, 2015 - 2026 (USD Million)
7.5.2.2 China G-protein coupled receptors (GPCR) market, by assay type, 2015 - 2026 (USD Million)
7.5.2.3 China G-protein coupled receptors (GPCR) market, by application, 2015 - 2026 (USD Million)
7.5.3 India
7.5.3.1 India G-protein coupled receptors (GPCR) market, by product, 2015 - 2026 (USD Million)
7.5.3.2 India G-protein coupled receptors (GPCR) market, by assay type, 2015 - 2026 (USD Million)
7.5.3.3 India G-protein coupled receptors (GPCR) market, by application, 2015 - 2026 (USD Million)
7.5.4 Japan
7.5.4.1 Japan G-protein coupled receptors (GPCR) market, by product, 2015 - 2026 (USD Million)
7.5.4.2 Japan G-protein coupled receptors (GPCR) market, by assay type, 2015 - 2026 (USD Million)
7.5.4.3 Japan G-protein coupled receptors (GPCR) market, by application, 2015 - 2026 (USD Million)
7.6 Latin America
7.6.1 Latin America G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million)
7.6.2 Brazil
7.6.2.1 Brazil G-protein coupled receptors (GPCR) market, by product, 2015 - 2026 (USD Million)
7.6.2.2 Brazil G-protein coupled receptors (GPCR) market, by assay type, 2015 - 2026 (USD Million)
7.6.2.3 Brazil G-protein coupled receptors (GPCR) market, by application, 2015 - 2026 (USD Million)
7.7 Middle East & Africa (MEA)
7.7.1 Middle east & africa G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million)
7.7.2 South africa
7.7.2.1 South Africa G-protein coupled receptors (GPCR) market, by product, 2015 - 2026 (USD Million)
7.7.2.2 South Africa G-protein coupled receptors (GPCR) market, by assay type, 2015 - 2026 (USD Million)
7.7.2.3 South Africa G-protein coupled receptors (GPCR) market, by application, 2015 - 2026 (USD Million)
Chapter 8 G-Protein Coupled Receptors (GPCR) Market Categorization: Competitive Analysis
8.1 Key Global Players, Recent Developments & Impact on the Industry
8.2 Key Company Categorization
8.3 Vendor Landscape
8.4 Public Companies
8.4.1 Company market position analysis
8.4.2 Competitive dashboard analysis
8.5 Private Companies
8.5.1 List of key emerging companies
Chapter 9 Competitive Landscape
9.1 Strategy Framework
9.2 Market Participation Categorization
9.3 Company Profiles
9.3.1 Thermo Fisher Scientific
9.3.1.1 Company overview
9.3.1.2 Financial performance
9.3.1.3 Product benchmarking
9.3.1.4 Strategic initiatives
9.3.2 Eurofins Scientific
9.3.2.1 Company overview
9.3.2.2 DiscoverX
9.3.2.2.1 Company overview
9.3.2.3 Financial performance
9.3.2.4 Product benchmarking
9.3.2.5 Strategic initiatives
9.3.3 QIAGEN
9.3.3.1 Company overview
9.3.3.2 Financial performance
9.3.3.3 Product benchmarking
9.3.3.4 Strategic initiatives
9.3.4 WuXi AppTec
9.3.4.1 Company overview
9.3.4.2 HD Biosciences Co. Ltd.
9.3.4.2.1 Company overview
9.3.4.3 Financial performance
9.3.4.4 Product benchmarking
9.3.4.5 Strategic initiatives
9.3.5 Promega Corporation
9.3.5.1 Company overview
9.3.5.2 Financial performance
9.3.5.3 Product benchmarking
9.3.5.4 Strategic initiatives
9.3.6 Abcam plc
9.3.6.1 Company overview
9.3.6.2 Financial performance
9.3.6.3 Product benchmarking
9.3.6.4 Strategic initiatives
9.3.7 Merck KGaA
9.3.7.1 Company overview
9.3.7.2 Financial performance
9.3.7.3 Product benchmarking
9.3.7.4 Strategic initiatives
9.3.8 PerkinElmer Inc.
9.3.8.1 Company overview
9.3.8.2 Cisbio Bioassays
9.3.8.2.1 Company overview
9.3.8.3 Financial performance
9.3.8.4 Product benchmarking
9.3.8.5 Strategic initiatives
9.3.9 Enzo Biochem Inc.
9.3.9.1 Company overview
9.3.9.2 Enzo Life Sciences, Inc.
9.3.9.2.1 Company overview
9.3.9.3 Financial performance
9.3.9.4 Product benchmarking
9.3.9.5 Strategic initiatives
9.3.10 Becton-Dickinson and Company
9.3.10.1 Company overview
9.3.10.2 Financial performance
9.3.10.3 Product benchmarking
9.3.10.4 Strategic initiatives
9.4 List of Companies
List of Tables Table 1 List of secondary sources Table 2 North America G-protein coupled receptors market estimates& forecasts, by product, 2015 - 2026 (USD Million) Table 3 North America G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 4 North America G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 5 U.S. G-protein coupled receptors market estimates& forecasts, by product, 2015 - 2026 (USD Million) Table 6 U.S. G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 7 U.S. G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 8 Canada G-protein coupled receptors market estimates& forecasts, by product, 2015 - 2026 (USD Million) Table 9 Canada G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 10 Canada G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 11 Europe G-protein coupled receptors market estimates& forecasts, by product, 2015 - 2026 (USD Million) Table 12 Europe G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 13 Europe G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 14 Germany G-protein coupled receptors market estimates& forecasts, by product, 2015 - 2026 (USD Million) Table 15 Germany G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 16 Germany G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 17 U.K. G-protein coupled receptors market estimates& forecasts, by product, 2015 - 2026 (USD Million) Table 18 U.K. G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 19 U.K. G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 20 Asia Pacific G-protein coupled receptors market estimates& forecasts, by product, 2015 - 2026 (USD Million) Table 21 Asia Pacific G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 22 Asia Pacific G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 23 China G-protein coupled receptors market estimates& forecasts, by product, 2015 - 2026 (USD Million) Table 24 China G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 25 China G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 26 India G-protein coupled receptors market estimates& forecasts, by product, 2015 - 2026 (USD Million) Table 27 India G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 28 India G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 29 Japan G-protein coupled receptors market estimates& forecasts, by product, 2015 - 2026 (USD Million) Table 30 Japan G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 31 Japan G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 32 Latin America G-protein coupled receptors market estimates& forecasts, by product, 2015 - 2026 (USD Million) Table 33 Latin America G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 34 Latin America G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 35 Brazil G-protein coupled receptors market estimates& forecasts, by product, 2015 - 2026 (USD Million) Table 36 Brazil G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 37 Brazil G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 38 Middle East & Africa G-protein coupled receptors market estimates& forecasts, by product, 2015 - 2026 (USD Million) Table 39 Middle East & Africa G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 40 Middle East & Africa G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 41 South Africa G-protein coupled receptors market estimates& forecasts, by product, 2015 - 2026 (USD Million) Table 42 South Africa G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 43 South Africa G-protein coupled receptors market estimates& forecasts, by assay type, 2015 - 2026 (USD Million) Table 44 List of private companies
List of Figures Fig. 1 Estimates and forecast timeline Fig. 2 Market research process Fig. 3 Information procurement Fig. 4 Primary research pattern Fig. 5 Market research approaches Fig. 6 Value-chain-based sizing & forecasting Fig. 7 QFD modeling for market share assessment Fig. 8 Market formulation & validation Fig. 9 G-protein coupled receptors market: Market segmentation & scope Fig. 10 G-protein coupled receptors market: Market snapshot Fig. 11 Penetration & growth prospect mapping for assay type, 2018 Fig. 12 Market trends & outlook Fig. 13 Market driver relevance analysis (Current & future impact) Fig. 14 Market restraint relevance analysis (Current & future impact) Fig. 15 Porter's Five Forces Analysis Fig. 16 SWOT analysis, by factor (political & legal, economic and technological) Fig. 17 G-protein coupled receptors (GPCR) market: Product outlook key takeaways Fig. 18 G-protein coupled receptors (GPCR) market: Product movement analysis Fig. 19 Global GPCR cell lines market, 2015 - 2026 (USD Million) Fig. 20 Global GPCR detection kits market, 2015 - 2026 (USD Million) Fig. 21 Global GPCR cell culture reagents market, 2015 - 2026 (USD Million) Fig. 22 Global GPCR ligands market, 2015 - 2026 (USD Million) Fig. 23 G-protein coupled receptors (GPCR) market: Assay type outlook key takeaways Fig. 24 G-protein coupled receptors (GPCR) market: Assay type movement analysis Fig. 25 Global cAMP functional assays market, 2015 - 2026 (USD Million) Fig. 26 Global calcium functional assays market, 2015 - 2026 (USD Million) Fig. 27 Global ?-arrestin functional assays market, 2015 - 2026 (USD Million) Fig. 28 Global radioligand binding and GTP?S functional assays market, 2015 - 2026 (USD Million) Fig. 29 Global internalization assays market, 2015 - 2026 (USD Million) Fig. 30 Global trafficking assays market, 2015 - 2026 (USD Million) Fig. 31 Global other GPCR assays market, 2015 - 2026 (USD Million) Fig. 32 G-protein coupled receptors (GPCR) market: Application outlook key takeaways Fig. 33 G-protein coupled receptors (GPCR) market: Application movement analysis Fig. 34 Global GPCR assays market for cancer research , 2015 - 2026 (USD Million) Fig. 35 Global GPCR assays market for central nervous system (CNS) research , 2015 - 2026 (USD Million) Fig. 36 Global GPCR assays market for metabolic research, 2015 - 2026 (USD Million) Fig. 37 Global GPCR Assays market for cardiovascular research, 2015 - 2026 (USD Million) Fig. 38 Global GPCR assays market for respiratory research, 2015 - 2026 (USD Million) Fig. 39 Global trafficking assays market, 2015 - 2026 (USD Million) Fig. 40 Global GPCR assays market for other applications , 2015 - 2026 (USD Million) Fig. 41 Regional market place: Key takeaway Fig. 42 G-protein coupled receptors regional outlook, 2018 & 2026 Fig. 43 North America G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million) Fig. 44 U.S. G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million) Fig. 45 Canada G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million) Fig. 46 Europe G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million) Fig. 47 Germany G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million) Fig. 48 U.K. G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million) Fig. 49 Asia Pacific G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million) Fig. 50 China G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million) Fig. 51 India G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million) Fig. 52 Japan G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million) Fig. 53 Latin America G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million) Fig. 54 Brazil G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million) Fig. 55 Middle East & Africa G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million) Fig. 56 South Africa G-protein coupled receptors (GPCR) market, 2015 - 2026 (USD Million) Fig. 57 Impact Analysis by key companies Fig. 58 Global G-protein coupled receptor market: Company Categorization Fig. 59 Competitive dashboard analysis for Public players Fig. 60 Strategy framework Fig. 61 Participant categorization Fig. 62 List of companies
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