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Biodegradable Stents

Published: Apr, 2015 | Pages: 148 | Publisher: RESEARCH IMPACT TECHNOLOGIES
Industry: Biotechnology | Report Format: Electronic (PDF)

This study gives an insight into Global Stents and Biodegradable Stents market. The report also provides an overview of the Worldwide Bare Metal Stents and Drug Eluting Stents market. Market analytics for Biodegradable Stents by Application and by Biodegradable Material is provided in this niche report. The market is divided by Application into Coronary Arterial Stents, Peripheral Arterial Stents and Other; and by Biodegradable Material into Polymer and Metal. Global stents market is analyzed from 2005 -2015, while estimations and predictions for biodegradable stents market are provided from 2015-2020. Key market dynamics are provided for North America, Europe, Asia-Pacific, and Rest of World (RoW).  Business profiles of 25 biodegradable stents companies are discussed in the report. Information related to recent product releases, product developments, partnerships, collaborations, and mergers and acquisitions is also covered in the report.
 Table of Content

1. SCOPE AND METHODOLOGY	1
2. REPORT SYNOPSIS	3
2.1 Introduction	3
Types of Stents	3
Bare-Metal Stents	4
Drug Eluting Stents (DES)	4
Everolimus	5
Sirolimus	5
Biolimus A9	5
Pimecrolimus	6
Biodegradable Stents	7
Raw Materials	7
Polymeric Stents	7
Degradation of Biodegradable Polymers	8
Processing of Biodegradable Polymers	9
Role of Biodegradable Polymers	9
In Tissue Engineering	9
In Controlling Drug Delivery	9
Application	10
Polymer based Stents	10
Igaki-Tamai Stent	10
ReZolve Stent	10
Metal Stents	11
Bioabsorbable Metal based Stents	12
Magnesium Stents	12
Applications of Biodegradable Stents	12
2.2 Segmentation	13
Exhibit 1. Segmentation of Biodegradable Stents Market by Application Area (2015 - 2020)	13
2.3 Stents - Global Market Analysis	14
Exhibit 2. Stents - Global Value Market Estimations & Predictions (2005 -2020) in US$ Billion	14
2.3 Biodegradable Stents - Global Market Analysis	15
Exhibit 3. Biodegradable Stents - Global Value Market Estimations & Predictions (2015 -2020) in US$ Million	15
Exhibit 4. List of Global Major Companies in Biodegradable Stents Market	15
3. MARKET DYNAMICS	17
3.1 Global Biodegradable Stents Market	17
Exhibit 5. Biodegradable Stents – Global Value Market Estimations & Predictions (2015 -2020) by Geographic Region for North America, Europe, Asia-Pacific and Rest of World in US$ Million	17
Exhibit 6. Biodegradable Stents – Global Value Market Shares (2015 & 2020) by Geographic Region for North America, Europe, Asia-Pacific and Rest of World	18
Exhibit 7. Biodegradable Stents – Global Value Market Estimations & Predictions (2015 -2020) by Application Area for Coronary Arterial Disease, Peripheral Arterial Disease and Other in US$ Million	19
Exhibit 8. Biodegradable Stents – Global Value Market Shares (2015 & 2020) by Application Area for Coronary Arterial Disease, Peripheral Arterial Disease and Other	20
3.4 Biodegradable Stents - Major Company Profiles	21
480 Biomedical (USA)	21
Abbott Vascular (USA)	22
American Medical Systems, Inc. (USA)	23
Arterial Remodeling Technologies (ART) (France)	23
Arterius Ltd. (UK)	24
Biotronik SE & Co. KG (Germany)	25
Boston Scientific Corporation (USA)	26
Bristol-Myers Squibb Company (USA)	27
Cedars-Sinai Medical Center (USA)	27
Cordis Corporation (USA)	28
Duke University (USA)	28
Elixir Medical Corporation (USA)	29
ELLA-CS, s.r.o. (Czech Republic)	32
Ethicon, Inc. (USA)	33
Eurocor GmbH (Germany)	34
GP Medical, Inc. (Australia)	35
JMS Co., Ltd. (Japan)	35
Kyoto Medical Planning Co., Ltd. (Japan)	36
Medtronic, Inc. (USA)	37
Poly-Med, Inc. (USA)	38
ProFibrix B.V. (The Netherlands)	39
Reva Medical Inc. (USA)	39
Tepha, Inc. (USA)	40
Xenogenics Corporation (USA)	41
3.5 Major Activities/Product Launches	42
First implantation of Elixir Medical’s DESolve® Novolimus Eluting Coronary Scaffold System in Europe	42
BIOTRONIK Reports Use of First–in–Human Use of Bioabsorbable Magnesium DREAMS Scaffold	42
Elixir Reports Outstanding 1-year Results for Safety and Efficacy for 100% Bioresorbable DESolve® Novolimus Eluting Coronary Scaffold System	43
Elixir's DESolve® Novolimus Eluting Bioresorbable Coronary Scaffold System Certified by CE	43
Asian Heart Institute Conducts Angioplasty with New Generation Biodegradable Stent	44
Elixir Medical Finalizes the Enrollment for the DESolve Nx Pivotal Trial Carried Out for Fully Bioresorbable Coronary Scaffold System	44
REVA Medical Presents the First Follow-Up Imaging Assessment of the ReZolve® Scaffold	45
Arterial Remodeling Technologies (ART) Announces First Human Use of Its Bioresorbable Stent	45
Biotronik Announces Positive Results from BIOSOLVE-I trial	45
American Heart Association Reports Igaki Tamai Biodegradable Stent Safe for Long-Term Treatment of Coronary Artery Disease	46
Reva Medical’s ReZolve™ Stent Bring a New Revolution to Cardiology: Claims to Stop Heart Attacks before they Occur with Resorbable Stents	46
S3V Vascular Technologies Introduces first Bioabsorbable Endovascular Drug Coated Stent "3V-Avatar"in India	47
Abbott Initiates Clinical Trial to Evaluate and compare Absorb™ Bioresorbable Vascular Scaffold and Metallic Drug Eluting Stent	48
Abbott Begins Clinical Trials for ABSORB™ BTK, to treat Below-the-Knee Limb Ischemia	48
UK Medical Launches the First Ever Biodegradable Esophageal Stent	49
Abbott Announces the Success of International Clinical Trial of 'ABSORB', a Bioresorbable Vascular Scaffold in Japan.	49
Arterius Ltd. Signs a New Research Collaboration	49
Abbott Announces the Success of Second Trial of 'ABSORB', a Bioresorbable Vascular Scaffold	50
Abbott Announces the CE Marking on ABSORB in Europe, World's First Drug Eluting Bioresorbable Vascular Scaffold	50
Biodegradable Stent Implanted in India	51
Xenogenics Completes the Acquisition of the Assets of Ideal BioStent	51
Biodegradable Heart Stent Study Findings	51
ART Raises US$ 8.5M for Biodegradable Stents	52
IGAKI-TAMAI’s Bioabsorbable Stent Gains CE Mark Status for Peripheral Artery	52
Abbott Develops Effective Bioabsorbable Stent	53
3.6 Biodegradable Stents – Market Outlook	54
4. PRODUCT TECHNOLOGY/RESEARCH	56
4.1 Introduction	56
Exhibit 9. Comparative Features - Bare Metal Stent, Drug Eluting Stent and Biodegradable Stent	56
Design and Composition	57
Raw Materials for Biodegradable Stents Synthesis	58
Biopolymers Used in Stents	58
Controlling properties	59
Mechanical performance	59
The chemistry of polymers	60
The selection of the materials	60
The steps in the processing	61
The degradations aspects	61
Exhibit 10. Characteristics of Widely Used Biodegradable polymers	61
Poly Lactic Acid	62
SR-PLA- Biodegradable Stents	63
Poly-Caprolactone	63
Polyglycolide	63
Biodegradable Metallic Stents	63
Iron-based Biodegradable Stents	64
Magnesium-based Biodegradable Stents	66
Fabrication of Biodegradable Stents	68
Exhibit 11. Biodegradable Stents – By Degradation Time and Biodegradable Material Used	68
Powder Metallurgy	69
Electroforming	69
Passivation Methods	70
Oxide Films	70
Electropolishing	70
Coatings	70
Nitinol & its Biocompatibility	71
Effect of Surface Passivation on Biocompatibility	71
Welding	73
Time Factor	73
Mechanical Property of Biodegradable Stents	74
Polymer Mechanical Property	74
Polymer Degradation	74
Comparison of Biodegradable Stents with Other Stents	75
Cost	75
Significance of Clinical Trials	76
Drug for Biodegradable Stents	76
Heparin	76
Sirolimus	77
Paclitaxel	77
Limitations	77
Advantages	77
Applications	78
Cardiovascular Disease	78
Ischemic Heart Disease	78
Congenital Heart Disease	79
Early Attempts to Treat CHD	79
4.2 Biodegradable Stents - Research Briefs	80
Biodegradable Magnesium Alloy for Medical Devices	80
A 59 year Old Implanted with Biodegradable Stent	80
Characteristics and Cyto-Compatibility of Biodegradable Polymer Film on Magnesium by Spin Coating	80
A Novel Radioplaque Biodegradable Stent for Pancreatobiliary Applications	81
Biodegradable Stent Found to be Safe for Long-term Therapy of Coronary Artery Disease	82
Biodegradable Stent proven to be Safe for Long-Term Treatment of Coronary Artery Disease	82
Biodegradable Stent and Hyper Granulation Causing Re-Stenosis Risk	83
Biodegradable Bifurcation Stents	83
Rabbit Airway Model Using New Biodegradable Polydioxanone Stents	84
Magnesium based bioabsorbable stents Inhibits Smooth Muscle Proliferation and Stimulates Endothelial Cells In Vitro	84
Biodegradable Stent for the Treatment of Benign Colorectal Anastomotic Stricture	85
In Vivo Study of Biodegradable Biliary Duct Stent	85
A New Potential Composite of MAO/PLLA using Modified Magnesium Alloy WE42 Developed	86
Use of Corrosion Model for Bioabsorbable Metallic Stents	87
New, Biodegradable Heart Stent Prove Safe in Trials	87
Clinical Follow-up Results of Biodegradable Stents (EXCEL™) and Durable Polymer Stent (CYPHER™) in Treating Coronary Artery Disease	87
Biodegradable Stents for Bronchial Stenosis Treatment	88
In Vivo Study of Biodegradable Poly (Trimethylene Carbonate-co-D, L-Lactide) Stent	88
Bio-Absorbable Stent for Treating CAD	89
Modeling of Deformation-Accelerated Breakdown of Polylactic Acid Biodegradable Stents	90
Biodegradable Stents for the First Time in India	90
The BEST (Biodegradable Esophageal Stent) study	91
Biodegradable Cardiovascular Stent Material Developed Using Electroformed Iron	91
Polydioxanone Biodegradable Stents for the Management of Benign Intrahepatic Bile Duct Strictures	92
Tomography Study of a Biodegradable Stents compared to Durable Polymer-Coated Limus –Eluting Stent	92
Coating Bio-Absorption and Chronic Bare Metal Scaffolding versus Fully Bio-Absorbable Stent	93
Researcher Develops Biodegradable Stent for Hearts Patients	93
Biodegradable Stent and Severe Epithelial Hyperplasia Complication	94
A Potential, Non-Randomized Multicenter Clinical Trial of Absorbable Magnesium Stents for Coronary Implants	94
Biodegradable Heart Stents	95
Absorbable Metal Stents	95
Drug-Eluting and Absorbable Stents Push Interventional Frontiers Separate Study Fine-Tunes Timing of Anti-Clotting Drugs	96
First Successful Implantation of a Biodegradable Metal Stent into the Left Pulmonary Artery of a Preterm Baby	99
Implantation of the First Absorbable Metal Stents (AMS) in Humans	99
Assessment of a Dissolvable Urethral Drainage Stent in a Swine Model	100
Biodegradable Stents – A Disappearing Act	101
Biodegradable Polyglycolic Acid Spiral Stent and Endoscopic Urethroplasty	102
V. CORPORATE DIRECTORY	103
VI. PATENTS INFORMATION	105

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