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Amyloidosis - Pipeline Review, H2 2017

Published: Jul, 2017 | Pages: 157 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)

Amyloidosis - Pipeline Review, H2 2017

Summary

Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Amyloidosis - Pipeline Review, H2 2017, provides an overview of the Amyloidosis (Metabolic Disorders) pipeline landscape.

Abnormal accumulation of amyloid protein in the tissues results in a group of diseases known as amyloidosis. It may affect the shape and functioning of the organ eventually leading to organ failure. Predisposing factors are misfolding of abnormal protein called the light chain and its subsequent deposition in the body. It may also occur as a result of dialysis. Symptoms include fatigue, chest pain, swelling and breathing problems. Amyloidosis can be managed by transplant and, medication such as diuretics and chemotherapy drugs. 

Report Highlights

Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Amyloidosis - Pipeline Review, H2 2017, provides comprehensive information on the therapeutics under development for Amyloidosis (Metabolic Disorders), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Amyloidosis (Metabolic Disorders) pipeline guide also reviews of key players involved in therapeutic development for Amyloidosis and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Pre-Registration, Filing rejected/Withdrawn, Phase III, Phase II, Phase I, Preclinical and Discovery stages are 1, 1, 4, 7, 7, 6 and 4 respectively. Similarly, the Universities portfolio in Phase II, Preclinical and Discovery stages comprises 1, 2 and 3 molecules, respectively.

Amyloidosis (Metabolic Disorders) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

- The pipeline guide provides a snapshot of the global therapeutic landscape of Amyloidosis (Metabolic Disorders).
- The pipeline guide reviews pipeline therapeutics for Amyloidosis (Metabolic Disorders) by companies and universities/research institutes based on information derived from company and industry-specific sources. 
- The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
- The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
- The pipeline guide reviews key companies involved in Amyloidosis (Metabolic Disorders) therapeutics and enlists all their major and minor projects.
- The pipeline guide evaluates Amyloidosis (Metabolic Disorders) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
- The pipeline guide encapsulates all the dormant and discontinued pipeline projects. 
- The pipeline guide reviews latest news related to pipeline therapeutics for Amyloidosis (Metabolic Disorders)

Reasons To Buy

- Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
- Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
- Find and recognize significant and varied types of therapeutics under development for Amyloidosis (Metabolic Disorders).
- Classify potential new clients or partners in the target demographic.
- Develop tactical initiatives by understanding the focus areas of leading companies.
- Plan mergers and acquisitions meritoriously by identifying key players and it's most promising pipeline therapeutics.
- Formulate corrective measures for pipeline projects by understanding Amyloidosis (Metabolic Disorders) pipeline depth and focus of Indication therapeutics.
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
- Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.
 Table of Contents
Table of Contents 2 List of Tables 4 List of Figures 4 Introduction 5 Global Markets Direct Report Coverage 5 Amyloidosis - Overview 6 Amyloidosis - Therapeutics Development 7 Pipeline Overview 7 Pipeline by Companies 8 Pipeline by Universities/Institutes 11 Products under Development by Companies 12 Products under Development by Universities/Institutes 14 Amyloidosis - Therapeutics Assessment 15 Assessment by Target 15 Assessment by Mechanism of Action 17 Assessment by Route of Administration 19 Assessment by Molecule Type 21 Amyloidosis - Companies Involved in Therapeutics Development 23 Alnylam Pharmaceuticals Inc 23 Amgen Inc 23 Arcturus Therapeutics Inc 24 Bsim2 24 Celgene Corp 25 GlaxoSmithKline Plc 25 Ionis Pharmaceuticals Inc 26 Johnson & Johnson 26 Millennium Pharmaceuticals Inc 27 Neurimmune Holding AG 27 Novartis AG 28 Oncopeptides AB 28 Pfizer Inc 29 Prothena Corp Plc 29 R Pharm 30 Regeneron Pharmaceuticals Inc 30 SOM Biotech SL 31 Spectrum Pharmaceuticals Inc 31 Amyloidosis - Drug Profiles 32 AG-10 - Drug Profile 32 ALN-ANG - Drug Profile 33 ALN-TTRsc02 - Drug Profile 34 CAEL-101 - Drug Profile 35 canakinumab - Drug Profile 37 carfilzomib - Drug Profile 43 CLR-01 - Drug Profile 55 daratumumab - Drug Profile 57 dezamizumab - Drug Profile 73 dezamizumab + GSK-2315698 - Drug Profile 74 doxycycline hyclate - Drug Profile 75 EDE-1307 - Drug Profile 76 GSK-2315698 - Drug Profile 77 GSK-3039294 - Drug Profile 78 inotersen sodium - Drug Profile 79 ixazomib citrate - Drug Profile 83 LUNAR-TTR - Drug Profile 93 melphalan - Drug Profile 94 melphalan flufenamide - Drug Profile 98 Monoclonal Antibody to Inhibit ATTR for Familial Amyloid Polyneuropathy - Drug Profile 100 Monoclonal Antibody to Target CD66b for Blood Cancer and Metabolic Disorders - Drug Profile 101 NEOD-001 - Drug Profile 102 NI-301 - Drug Profile 107 NPT-289 - Drug Profile 108 Oligonucleotides to Inhibit Transthyretin for Amyloidosis - Drug Profile 109 patisiran - Drug Profile 110 pomalidomide - Drug Profile 118 PRX-004 - Drug Profile 125 RPH-104 - Drug Profile 126 Small Molecule to Inhibit Amyloid Beta Peptide for Alzheimer's Disease and Amyloidosis - Drug Profile 127 Small Molecules to Activate ATF6 for Amyloidosis - Drug Profile 128 Small Molecules to Inhibit Transthyretin for Familial Amyloid Polyneuropathy - Drug Profile 129 Small Molecules to Inhibit Transthyretin Related Amyloid Protein for Familial Amyloidotic Cardiomyopathy - Drug Profile 130 Small Molecules to Inhibit Transthyretin Related Amyloid Protein for Familial Amyloidotic Polyneuropathy - Drug Profile 131 tafamidis meglumine - Drug Profile 132 tolcapone - Drug Profile 135 Amyloidosis - Dormant Projects 137 Amyloidosis - Discontinued Products 138 Amyloidosis - Product Development Milestones 139 Featured News & Press Releases 139 Appendix 153 Methodology 153 Coverage 153 Secondary Research 153 Primary Research 153 Expert Panel Validation 153 Contact Us 153 Disclaimer 154
List of Tables
Number of Products under Development for Amyloidosis, H2 2017 Number of Products under Development by Companies, H2 2017 Number of Products under Development by Companies, H2 2017 (Contd..1), H2 2017 Number of Products under Development by Universities/Institutes, H2 2017 Products under Development by Companies, H2 2017 Products under Development by Companies, H2 2017 (Contd..1), H2 2017 Products under Development by Universities/Institutes, H2 2017 Number of Products by Stage and Target, H2 2017 Number of Products by Stage and Mechanism of Action, H2 2017 Number of Products by Stage and Route of Administration, H2 2017 Number of Products by Stage and Molecule Type, H2 2017 Amyloidosis - Pipeline by Alnylam Pharmaceuticals Inc, H2 2017 Amyloidosis - Pipeline by Amgen Inc, H2 2017 Amyloidosis - Pipeline by Arcturus Therapeutics Inc, H2 2017 Amyloidosis - Pipeline by Bsim2, H2 2017 Amyloidosis - Pipeline by Celgene Corp, H2 2017 Amyloidosis - Pipeline by GlaxoSmithKline Plc, H2 2017 Amyloidosis - Pipeline by Ionis Pharmaceuticals Inc, H2 2017 Amyloidosis - Pipeline by Johnson & Johnson, H2 2017 Amyloidosis - Pipeline by Millennium Pharmaceuticals Inc, H2 2017 Amyloidosis - Pipeline by Neurimmune Holding AG, H2 2017 Amyloidosis - Pipeline by Novartis AG, H2 2017 Amyloidosis - Pipeline by Oncopeptides AB, H2 2017 Amyloidosis - Pipeline by Pfizer Inc, H2 2017 Amyloidosis - Pipeline by Prothena Corp Plc, H2 2017 Amyloidosis - Pipeline by R Pharm, H2 2017 Amyloidosis - Pipeline by Regeneron Pharmaceuticals Inc, H2 2017 Amyloidosis - Pipeline by SOM Biotech SL, H2 2017 Amyloidosis - Pipeline by Spectrum Pharmaceuticals Inc, H2 2017 Amyloidosis - Dormant Projects, H2 2017 Amyloidosis - Discontinued Products, H2 2017



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