ADME Toxicology Testing Market Analysis Report By Technology (Cell Culture, OMICS Tech), By Application (Systemic Toxicity, Renal Toxicity), By Method, By Region, And Segment Forecasts, 2018 - 2025

Published: Nov, 2018 | Pages: 149 | Publisher: Grand View Research
Industry: Biotechnology | Report Format: Electronic (PDF)

The global ADME toxicology testing market size is expected to generate a revenue of USD 10.25 billion by 2025, according to a new report by Grand View Research, Inc., exhibiting a CAGR of 11.4% during the forecast period. Factors such as increased need to check late-stage drug failures with adoption of more appropriate toxicity testing methods by pharmaceutical companies is expected to aid revenue generation for the market.

Absorption, distribution, metabolism, and excretion (ADME) toxicology testing is used to test toxic reactions caused by molecules in clinical trials on factors and systemic reactions such as chemical, pharmaceutical, and genetic. These toxicology testing procedures help in effective drug development, which limits or prevents toxic reactions to the body when administered. Toxicity levels are decided on the results of a series of tests conducted in near natural conditions, which represent almost real-time reactions between the drug and host.

As of 2017, approximately 43.0% of ADME toxicology testing areas carried out are based on cell culture tech. Cell culture technology is adopted widely owing to advantages such as near natural conditions and accurate results obtained at a cellular level.

These assays are conducted for several types of toxic reactions or systems where toxic reactions might take place. Some of the toxicity tests are systemic toxicity, renal toxicity, hepatotoxicity, neurotoxicity, and other toxicities that might result in a living tissue. Advancements in testing methods are underway and this trend is likely to be picked up by many companies developing drug molecules. This will speed up the drug discovery process and boost market growth.

Further key findings from the report suggest:

• The market is driven by increasing ratio of late-stage drug failures, resulting in loss of valuable time and investment for drug development. Growth and increasing adoption of OMICS technology is also expected to boost revenue generation in the coming years

• North America is the largest market for ADME toxicology testing owing to presence of large number of pharmaceutical companies competing for commercial launch of novel molecules

• Developing regions of Asia Pacific and Latin America are set to grow considerably as many multinational and local players are striving to enter the market. They are also looking improve their hold in markets that present innovation and growth opportunities

• Some of the key players in this market are Accelrys Inc.; Agilent Technologies, Inc.; Albany Molecular Research Inc.; Beckman Coulter Inc.; Catalent Inc.; Charles River Laboratories International Inc.; AbbVie; Actelion Pharmaceuticals; Amgen; Biocon; BioMarin; Boehringer Ingelheim; Bristol-Myers Squibb; Cipla; and CymaBay Therapeutics.

 Table of Contents

Chapter 1 Research Methodology
                 1.1 Information Procurement
                 1.2 Data Analysis

Chapter 2 Executive Summary
                 2.1 Market Snapshot

Chapter 3 Market Variables, Trends & Scope
                 3.1 Market segmentation & scope
                     3.1.1 Market driver Analysis
                         3.1.1.1 High rate of late stage drug failure
                         3.1.1.2 Increasing need for novel drug molecules
                         3.1.1.3 Technological advancements
                     3.1.2 Market restraint analysis
                         3.1.2.1 Decreasing investments in drug development
                 3.2 Penetration & growth prospect mapping
                 3.3 ADME toxicology testing - SWOT Analysis, By Factor (political & legal, economic and technological)
                 3.4 Industry Analysis - Porter's

Chapter 4 ADME toxicology testing Market: Technology Estimates & Trend Analysis
                 4.1 ADME toxicology testing market by technology, movement analysis
                 4.2 Cell Culture Technology
                     4.2.1 Cell culture technology market estimates and forecast, 2014 - 2025 (USD Million)
                 4.3 High Throughput Technology
                     4.3.1 High throughput technology market estimates and forecast, 2014 - 2025 (USD Million)
                 4.4 Molecular Imaging
                     4.4.1 Molecular imaging market estimates and forecast, 2014 - 2025 (USD Million)
                 4.5 OMICS Technology
                     4.5.1 OMICS technology estimates and forecast, 2014 - 2025 (USD Million)

Chapter 5 ADME toxicology testing Market: Method Estimates & Trend Analysis
                 5.1 ADME toxicology testing market: method movement analysis
                 5.2 Cellular Assay
                     5.2.1 Cellular assay market estimates and forecast, 2014 - 2025 (USD Million)
                 5.3 Biochemical Assay
                     5.3.1 Biochemical assays market estimates and forecast, 2014 - 2025 (USD Million)
                 5.4 In-Silico Assays
                     5.4.1 In-Silico assays market estimates and forecast, 2014 - 2025 (USD Million)
                 5.5 Ex-Vivo Assays
                     5.5.1 Ex-Vivo assays market estimates and forecast, 2014 - 2025 (USD Million)

Chapter 6 ADME toxicology testing Market: Application Estimates & Trend Analysis
                 6.1 ADME toxicology testing market: application movement analysis
                 6.2 Systemic Toxicity
                     6.2.1 Systemic toxicity market estimates and forecast, 2014 - 2025 (USD Million)
                 6.3 Renal Toxicity
                     6.3.1 Renal toxicity market estimates and forecast, 2014 - 2025 (USD Million)
                 6.4 Hepatotoxicity
                     6.4.1 Hepatotoxicity market estimates and forecast, 2014 - 2025 (USD Million)
                 6.5 Neurotoxicity
                     6.5.1 Neurotoxicity market estimates and forecast, 2014 - 2025 (USD Million)
                 6.6 Other Toxicity
                     6.6.1 Other toxicity market estimates and forecast, 2014 - 2025 (USD Million)

Chapter 7 ADME toxicology testing Market: Regional Outlook
                 7.1 ADME toxicology testing market share by region, 2017 & 2025 (USD Million)
                 7.2 North America
                     7.2.1 North America market estimates and forecast, 2014 - 2025 (USD Million)
                     7.2.2 U.S.
                         7.2.2.1 U.S. ADME toxicology testing market, 2014 - 2025 (USD Million)
                     7.2.3 Canada
                         7.2.3.1 Canada ADME toxicology testing market, 2014 - 2025 (USD Million)
                 7.3 Europe
                     7.3.1 Europe ADME toxicology testing market, 2014 - 2025 (USD Million)
                     7.3.2 U.K.
                         7.3.2.1 U.K. ADME toxicology testing market, 2014 - 2025 (USD Million)
                     7.3.3 Germany
                         7.3.3.1 Germany ADME toxicology testing market, 2014 - 2025 (USD Million)
                 7.4 Asia Pacific
                     7.4.1 Asia Pacific ADME toxicology testing market, 2014 - 2025 (USD Million)
                     7.4.2 Japan
                         7.4.2.1 Japan ADME toxicology testing market, 2014 - 2025 (USD Million)
                     7.4.3 China
                         7.4.3.1 China ADME toxicology testing market, 2014 - 2025 (USD Million)
                 7.5 Latin America
                     7.5.1 Latin America ADME toxicology testing market, 2014 - 2025 (USD Million)
                     7.5.2 Brazil
                         7.5.2.1 Brazil ADME toxicology testing market, 2014 - 2025 (USD Million)
                 7.6 MEA
                     7.6.1 MEA ADME toxicology testing market, 2014 - 2025 (USD Million)
                     7.6.2 South Africa
                         7.6.2.1 South Africa ADME toxicology testing market, 2014 - 2025 (USD Million)

Chapter 8 Competitive Landscape
                 8.1 Strategy Framework
                 8.2 Market Participation Categorization
                 8.3 Company Profiles
                     8.3.1 Thermo Fisher Scientific Inc.,
                         8.3.1.1 Company overview
                         8.3.1.2 Financial performance
                         8.3.1.3 Product benchmarking
                         8.3.1.4 Strategic initiatives
                     8.3.2 Promega Corporation
                         8.3.2.1 Company overview
                         8.3.2.2 Financial performance
                         8.3.2.3 Product benchmarking
                     8.3.3 Agilent Technologies
                         8.3.3.1 Company overview
                         8.3.3.2 Financial performance
                         8.3.3.3 Product benchmarking
                         8.3.3.4 Strategic initiatives
                     8.3.4 Albany Molecular Research Inc.,
                         8.3.4.1 Company Overview
                         8.3.4.2 Financial performance
                         8.3.4.3 Product Benchmarking
                         8.3.4.4 Strategic Initiatives
                     8.3.5 Accelrys, Inc., (Dassault Systemes BIOVIA)
                         8.3.5.1 Company Overview
                         8.3.5.2 Financial Information
                         8.3.5.3 Product Benchmarking
                         8.3.5.4 Strategic Initiatives
                     8.3.6 Beckman Coulter, Inc., (Danaher)
                         8.3.6.1 Company overview
                         8.3.6.2 Financial performance
                         8.3.6.3 Product benchmarking
                         8.3.6.4 Strategic Initiatives
                     8.3.7 Catalent
                         8.3.7.1 Company overview
                         8.3.7.2 Financial performance
                         8.3.7.3 Product benchmarking
                         8.3.7.4 Strategic Initiatives
                     8.3.8 Charles River Laboratories International, Inc.,
                         8.3.8.1 Company overview
                         8.3.8.2 Financial performance
                         8.3.8.3 Product benchmarking
                         8.3.8.4 Strategic Initiatives
                     8.3.9 Covance, Inc. (LabCorp)
                         8.3.9.1 Company overview
                         8.3.9.2 Financial performance
                         8.3.9.3 Product benchmarking
                         8.3.9.4 Strategic Initiatives
                     8.3.10 Eurofins Scientific SE
                         8.3.10.1 Company Overview
                         8.3.10.2 Financial performance
                         8.3.10.3 Product benchmarking
                         8.3.10.4 Strategic Initiatives
                     8.3.11 General Electric Company (Healthcare)
                         8.3.11.1 Company Overview
                         8.3.11.2 Financial performance
                         8.3.11.3 Product benchmarking
                         8.3.11.4 Strategic Initiatives
                     8.3.12 Life Technologies Corporation
                         8.3.12.1 Company Overview
                         8.3.12.2 Financial performance
                         8.3.12.3 Product benchmarking
                         8.3.12.4 Strategic Initiatives
                     8.3.13 Miltenyi Biotec
                         8.3.13.1 Company Overview
                         8.3.13.2 Financial performance
                         8.3.13.3 Product benchmarking
                         8.3.13.4 Strategic Initiatives
                     8.3.14 Quintiles
                         8.3.14.1 Company Overview
                         8.3.14.2 Financial performance
                         8.3.14.3 Product benchmarking
                         8.3.14.4 Strategic Initiatives

List of Tables

TABLE 1 North America ADME toxicology testing market, by technology scope, 2014 - 2025 (USD Million)
TABLE 2 North America ADME toxicology testing market, by method, 2014 - 2025 (USD Million)
TABLE 3 North America ADME toxicology testing market, by application, 2014 - 2025 (USD Million)
TABLE 4 U.S. ADME toxicology testing market, by technology scope, 2014 - 2025 (USD Million)
TABLE 5 U.S. ADME toxicology testing market, by method, 2014 - 2025 (USD Million)
TABLE 6 U.S. ADME toxicology testing market, by application, 2014 - 2025 (USD Million)
TABLE 7 Canada ADME toxicology testing market, by technology scope, 2014 - 2025 (USD Million)
TABLE 8 Canada ADME toxicology testing market, by method, 2014 - 2025 (USD Million)
TABLE 9 Canada ADME toxicology testing market, by application, 2014 - 2025 (USD Million)
TABLE 10 Europe ADME toxicology testing market, by technology scope, 2014 - 2025 (USD Million)
TABLE 11 Europe ADME toxicology testing market, by method, 2014 - 2025 (USD Million)
TABLE 12 Europe ADME toxicology testing market, by application, 2014 - 2025 (USD Million)
TABLE 13 U.K. ADME toxicology testing market, by technology scope, 2014 - 2025 (USD Million)
TABLE 14 U.K. ADME toxicology testing market, by method, 2014 - 2025 (USD Million)
TABLE 15 U.K. ADME toxicology testing market, by application, 2014 - 2025 (USD Million)
TABLE 16 Germany ADME toxicology testing market, by technology scope, 2014 - 2025 (USD Million)
TABLE 17 Germany ADME toxicology testing market, by method, 2014 - 2025 (USD Million)
TABLE 18 Germany ADME toxicology testing market, by application, 2014 - 2025 (USD Million)
TABLE 19 Asia Pacific ADME toxicology testing market, by technology scope, 2014 - 2025 (USD Million)
TABLE 20 Asia Pacific ADME toxicology testing market, by method, 2014 - 2025 (USD Million)
TABLE 21 Asia Pacific ADME toxicology testing market, by application, 2014 - 2025 (USD Million)
TABLE 22 Japan ADME toxicology testing market, by technology scope, 2014 - 2025 (USD Million)
TABLE 23 Japan ADME toxicology testing market, by method, 2014 - 2025 (USD Million)
TABLE 24 Japan ADME toxicology testing market, by application, 2014 - 2025 (USD Million)
TABLE 25 China ADME toxicology testing market, by technology scope, 2014 - 2025 (USD Million)
TABLE 26 China ADME toxicology testing market, by method, 2014 - 2025 (USD Million)
TABLE 27 China ADME toxicology testing market, by application, 2014 - 2025 (USD Million)
TABLE 28 Latin America ADME toxicology testing market, by technology scope, 2014 - 2025 (USD Million)
TABLE 29 Latin America ADME toxicology testing market, by method, 2014 - 2025 (USD Million)
TABLE 30 Latin America ADME toxicology testing market, by application, 2014 - 2025 (USD Million)
TABLE 31 Brazil ADME toxicology testing market, by technology scope, 2014 - 2025 (USD Million)
TABLE 32 Brazil ADME toxicology testing market, by method, 2014 - 2025 (USD Million)
TABLE 33 Brazil ADME toxicology testing market, by application, 2014 - 2025 (USD Million)
TABLE 34 MEA ADME toxicology testing market, by technology scope, 2014 - 2025 (USD Million)
TABLE 35 MEA ADME toxicology testing market, by method, 2014 - 2025 (USD Million)
TABLE 36 MEA ADME toxicology testing market, by application, 2014 - 2025 (USD Million)
TABLE 37 South Africa ADME toxicology testing market, by technology scope, 2014 - 2025 (USD Million)
TABLE 38 South Africa ADME toxicology testing market, by method, 2014 - 2025 (USD Million)
TABLE 39 South Africa ADME toxicology testing market, by application, 2014 - 2025 (USD Million)

List of Figures

FIG. 1 Market research process
FIG. 2 Information procurement
FIG. 3 Primary research pattern
FIG. 4 Market research approaches
FIG. 5 Value chain based sizing & forecasting
FIG. 6 QFD modelling for market share assessment
FIG. 7 Market summary
FIG. 8 Market trends & outlook
FIG. 9 Market segmentation & scope
FIG. 10 Market driver relevance analysis (Current & future impact)
FIG. 11 Market restraint relevance analysis (Current & future impact)
FIG. 12 Penetration & growth prospect mapping
FIG. 13 SWOT Analysis, By Factor (political & legal, economic and technological)
FIG. 14 Porter's Five Forces Analysis
FIG. 15 ADME toxicology testing market technology outlook
FIG. 16 ADME toxicology testing market: Product movement analysis
FIG. 17 Global cell culture technology market, 2014 - 2025 (USD Million)
FIG. 18 Global high throughput technology market, 2014 - 2025 (USD Million)
FIG. 19 Global molecular imaging market, 2014 - 2025 (USD Million)
FIG. 20 Global OMICS technology estimates and forecast, 2014 - 2025 (USD Million)
FIG. 21 ADME toxicology testing market method outlook key takeaways
FIG. 22 ADME toxicology testing market: method movement analysis
FIG. 23 Global cellular assay market, 2014 - 2025 (USD Million)
FIG. 24 Global biochemical assays market, 2014 - 2025 (USD Million)
FIG. 25 Global In-Silico assays market, 2014 - 2025 (USD Million)
FIG. 26 Global ex-vivo assays market, 2014 - 2025 (USD Million)
FIG. 27 ADME toxicology testing market: application outlook key takeaways
FIG. 28 ADME toxicology testing market: application movement analysis
FIG. 29 Global systemic toxicity market, 2014 - 2025 (USD Million)
FIG. 30 Global renal toxicity market, 2014 - 2025 (USD Million)
FIG. 31 Global hepatotoxicity market, 2014 - 2025 (USD Million)
FIG. 32 Global neurotoxicity market, 2014 - 2025 (USD Million)
FIG. 33 Global other toxicity market, 2014 - 2025 (USD Million)
FIG. 34 Regional market place: Key takeaways
FIG. 35 Regional outlook, 2017 & 2025
FIG. 36 North America ADME toxicology testing market, 2014 - 2025 (USD Million)
FIG. 37 U.S. ADME toxicology testing market, 2014 - 2025 (USD Million)
FIG. 38 Canada ADME toxicology testing market, 2014 - 2025 (USD Million)
FIG. 39 Europe ADME toxicology testing market, 2014 - 2025 (USD Million)
FIG. 40 U.K. ADME toxicology testing market, 2014 - 2025 (USD Million)
FIG. 41 Germany ADME toxicology testing market, 2014 - 2025 (USD Million)
FIG. 42 Asia Pacific ADME toxicology testing market, 2014 - 2025 (USD Million)
FIG. 43 Japan ADME toxicology testing market, 2014 - 2025 (USD Million)
FIG. 44 China ADME toxicology testing market, 2014 - 2025 (USD Million)
FIG. 45 Latin America ADME toxicology testing market, 2014 - 2025 (USD Million)
FIG. 46 Brazil ADME toxicology testing market, 2014 - 2025 (USD Million)
FIG. 47 MEA ADME toxicology testing market, 2014 - 2025 (USD Million)
FIG. 48 South Africa ADME toxicology testing market, 2014 - 2025 (USD Million)

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