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Published: Mar, 2015 | Pages:
93 | Publisher: Global Markets Direct
Industry: Oncology | Report Format: Electronic (PDF)
T-Cell Leukemia - Pipeline Review, H1 2015 Summary Global Markets Direct's, 'T-Cell Leukemia - Pipeline Review, H1 2015', provides an overview of the T-Cell Leukemia's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for T-Cell Leukemia, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for T-Cell Leukemia and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of T-Cell Leukemia - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for T-Cell Leukemia and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the T-Cell Leukemia products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the T-Cell Leukemia pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for T-Cell Leukemia - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding T-Cell Leukemia pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and Scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of table 5 List of Figures 6 Introduction 7 Global Markets Direct Report Coverage 7 T-Cell Leukemia Overview 8 Therapeutics Development 9 Pipeline Products for T-Cell Leukemia - Overview 9 Pipeline Products for T-Cell Leukemia - Comparative Analysis 10 T-Cell Leukemia - Therapeutics under Development by Companies 11 T-Cell Leukemia - Therapeutics under Investigation by Universities/Institutes 12 T-Cell Leukemia - Pipeline Products Glance 13 Clinical Stage Products 13 Early Stage Products 14 T-Cell Leukemia - Products under Development by Companies 15 T-Cell Leukemia - Products under Investigation by Universities/Institutes 16 T-Cell Leukemia - Companies Involved in Therapeutics Development 17 Applied Immune Technologies Ltd 17 Astellas Pharma Inc. 18 Bristol-Myers Squibb Company 19 Celgene Corporation 20 iDD biotech SAS 21 Kyowa Hakko Kirin Co., Ltd. 22 MediGene AG 23 Nippon Kayaku Co., Ltd. 24 Pfizer Inc. 25 Pharmacyclics, Inc. 26 Sanofi 27 Stemline Therapeutics, Inc. 28 Theravectys S.A. 29 Tolero Pharmaceuticals, Inc. 30 T-Cell Leukemia - Therapeutics Assessment 31 Assessment by Monotherapy Products 31 Assessment by Target 32 Assessment by Mechanism of Action 34 Assessment by Route of Administration 36 Assessment by Molecule Type 38 Drug Profiles 40 AGS-67E - Drug Profile 40 Product Description 40 Mechanism of Action 40 R&D Progress 40 alemtuzumab - Drug Profile 41 Product Description 41 Mechanism of Action 41 R&D Progress 41 Antibody to Inhibit HLA-A2 for Neurology, Infectious Diseases and T-Cell Leukemia - Drug Profile 44 Product Description 44 Mechanism of Action 44 R&D Progress 44 BMS-906024 - Drug Profile 45 Product Description 45 Mechanism of Action 45 R&D Progress 45 Cell Therapy to Target CD38 for cancer - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 IDD-003 - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 INA-01 - Drug Profile 49 Product Description 49 Mechanism of Action 49 R&D Progress 49 lenalidomide - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 MMIG-202 - Drug Profile 54 Product Description 54 Mechanism of Action 54 R&D Progress 54 mogamulizumab - Drug Profile 55 Product Description 55 Mechanism of Action 55 R&D Progress 55 Monoclonal Antibodies to Antagonize TCR for Leukemia and Autoimmune Disease - Drug Profile 57 Product Description 57 Mechanism of Action 57 R&D Progress 57 Monoclonal Antibody to Target CCR9 for T Lymphoblastic Leukemia - Drug Profile 58 Product Description 58 Mechanism of Action 58 R&D Progress 58 NK-314 - Drug Profile 59 Product Description 59 Mechanism of Action 59 R&D Progress 59 Oncolytic Virus to Target Glycoprotein gp160 for T-cell Leukemia - Drug Profile 60 Product Description 60 Mechanism of Action 60 R&D Progress 60 PCI-34051 - Drug Profile 61 Product Description 61 Mechanism of Action 61 R&D Progress 61 PF-03084014 - Drug Profile 62 Product Description 62 Mechanism of Action 62 R&D Progress 62 SL-101 - Drug Profile 64 Product Description 64 Mechanism of Action 64 R&D Progress 64 Synthetic Peptide for Oncology and Male health - Drug Profile 65 Product Description 65 Mechanism of Action 65 R&D Progress 65 THV-02 - Drug Profile 66 Product Description 66 Mechanism of Action 66 R&D Progress 66 TP-0903 - Drug Profile 67 Product Description 67 Mechanism of Action 67 R&D Progress 67 T-Cell Leukemia - Recent Pipeline Updates 68 T-Cell Leukemia - Dormant Projects 85 T-Cell Leukemia - Discontinued Products 86 T-Cell Leukemia - Product Development Milestones 87 Featured News & Press Releases 87 Feb 04, 2015: THERAVECTYS Obtains Orphan Drug Designation from the European Medicines Agency for Its Lentiviral Vector-Based Therapeutic Vaccine against Adult T-Cell Leukemia and Lymphoma 87 Dec 18, 2014: Approval for Additional Indication for Chemotherapy-Native CCR4-positive ATL of Mogamulizumab 88 Sep 29, 2014: Pfizer And Kyowa Hakko Kirin To Collaborate On Immuno-Oncology Combination Study 88 Aug 23, 2012: Kyowa Hakko Kirin Initiates Pivotal Phase II Trial Of Mogamulizumab In Patients With Adult T-cell Leukemia-Lymphoma In US And Europe 89 Jul 19, 2012: Application Seeking Approval for Additional Indication for ATL, PTCL and CTCL of Mogamulizumab 89 May 29, 2012: Kyowa Hakko Kirin Launches POTELIGEO Injection In Japan 90 Jan 25, 2012: Study Shows Leukemia Drug Kills Cancerous T-cells While Sparing Normal Immunity 90 Dec 07, 2010: Kyowa Hakko Kirin Announces Results From Japan Phase II Clinical Trial Of KW-0761 In Adult T-Cell Leukemia-Lymphoma 91 Appendix 92 Methodology 92 Coverage 92 Secondary Research 92 Primary Research 92 Expert Panel Validation 92 Contact Us 92 Disclaimer 93
List of Tables Number of Products under Development for T-Cell Leukemia, H1 2015 9 Number of Products under Development for T-Cell Leukemia - Comparative Analysis, H1 2015 10 Number of Products under Development by Companies, H1 2015 11 Number of Products under Investigation by Universities/Institutes, H1 2015 12 Comparative Analysis by Clinical Stage Development, H1 2015 13 Comparative Analysis by Early Stage Development, H1 2015 14 Products under Development by Companies, H1 2015 15 Products under Investigation by Universities/Institutes, H1 2015 16 T-Cell Leukemia - Pipeline by Applied Immune Technologies Ltd, H1 2015 17 T-Cell Leukemia - Pipeline by Astellas Pharma Inc., H1 2015 18 T-Cell Leukemia - Pipeline by Bristol-Myers Squibb Company, H1 2015 19 T-Cell Leukemia - Pipeline by Celgene Corporation, H1 2015 20 T-Cell Leukemia - Pipeline by iDD biotech SAS, H1 2015 21 T-Cell Leukemia - Pipeline by Kyowa Hakko Kirin Co., Ltd., H1 2015 22 T-Cell Leukemia - Pipeline by MediGene AG, H1 2015 23 T-Cell Leukemia - Pipeline by Nippon Kayaku Co., Ltd., H1 2015 24 T-Cell Leukemia - Pipeline by Pfizer Inc., H1 2015 25 T-Cell Leukemia - Pipeline by Pharmacyclics, Inc., H1 2015 26 T-Cell Leukemia - Pipeline by Sanofi, H1 2015 27 T-Cell Leukemia - Pipeline by Stemline Therapeutics, Inc., H1 2015 28 T-Cell Leukemia - Pipeline by Theravectys S.A., H1 2015 29 T-Cell Leukemia - Pipeline by Tolero Pharmaceuticals, Inc., H1 2015 30 Assessment by Monotherapy Products, H1 2015 31 Number of Products by Stage and Target, H1 2015 33 Number of Products by Stage and Mechanism of Action, H1 2015 35 Number of Products by Stage and Route of Administration, H1 2015 37 Number of Products by Stage and Molecule Type, H1 2015 39 T-Cell Leukemia Therapeutics - Recent Pipeline Updates, H1 2015 68 T-Cell Leukemia - Dormant Projects, H1 2015 85 T-Cell Leukemia - Discontinued Products, H1 2015 86
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