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Published: Jan, 2015 | Pages:
61 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Sarcopenia - Pipeline Review, H1 2015 Summary Global Markets Direct's, 'Sarcopenia - Pipeline Review, H1 2015', provides an overview of the Sarcopenia's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Sarcopenia, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Sarcopenia and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Sarcopenia - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Sarcopenia and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Sarcopenia products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Sarcopenia pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Sarcopenia - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Sarcopenia pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 5 List of Figures 5 Introduction 6 Global Markets Direct Report Coverage 6 Sarcopenia Overview 7 Therapeutics Development 8 Pipeline Products for Sarcopenia - Overview 8 Pipeline Products for Sarcopenia - Comparative Analysis 9 Sarcopenia - Therapeutics under Development by Companies 10 Sarcopenia - Therapeutics under Investigation by Universities/Institutes 11 Sarcopenia - Pipeline Products Glance 12 Clinical Stage Products 12 Early Stage Products 13 Sarcopenia - Products under Development by Companies 14 Sarcopenia - Products under Investigation by Universities/Institutes 15 Sarcopenia - Companies Involved in Therapeutics Development 16 Calzada Limited 16 Cytokinetics, Inc. 17 GlaxoSmithKline plc 18 Myos Corporation 19 Neurotune AG 20 Novartis AG 21 PsiOxus Therapeutics, Ltd. 22 Regeneron Pharmaceuticals, Inc. 23 Sumitomo Dainippon Pharma Co., Ltd. 24 Sarcopenia - Therapeutics Assessment 25 Assessment by Monotherapy Products 25 Assessment by Target 26 Assessment by Mechanism of Action 28 Assessment by Route of Administration 30 Assessment by Molecule Type 32 Drug Profiles 34 AOD-9604 - Drug Profile 34 Product Description 34 Mechanism of Action 34 R&D Progress 34 bimagrumab - Drug Profile 36 Product Description 36 Mechanism of Action 36 R&D Progress 36 CK-2066260 - Drug Profile 38 Product Description 38 Mechanism of Action 38 R&D Progress 38 MT-102 - Drug Profile 40 Product Description 40 Mechanism of Action 40 R&D Progress 40 NEP-28 - Drug Profile 42 Product Description 42 Mechanism of Action 42 R&D Progress 42 NT-1654 - Drug Profile 43 Product Description 43 Mechanism of Action 43 R&D Progress 43 Protein for Musculoskeletal Disorders - Drug Profile 44 Product Description 44 Mechanism of Action 44 R&D Progress 44 Recombinant Protein for Sarcopenia - Drug Profile 45 Product Description 45 Mechanism of Action 45 R&D Progress 45 REGN-1033 - Drug Profile 46 Product Description 46 Mechanism of Action 46 R&D Progress 46 S-107 - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 Small Molecules to Inhibit Furin for Sarcopenia and Cachexia - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 Small Molecules to Inhibit JAK3 for Sarcopenia and Cachexia - Drug Profile 49 Product Description 49 Mechanism of Action 49 R&D Progress 49 Sarcopenia - Recent Pipeline Updates 50 Sarcopenia - Dormant Projects 53 Sarcopenia - Discontinued Products 54 Sarcopenia - Product Development Milestones 55 Featured News & Press Releases 55 Mar 13, 2012: Calzada Announces Positive Results Of AOD9604 In Cartilage And Muscle Repair Models 55 Dec 14, 2011: Calzada Announces New Applications For AOD9604 55 Dec 08, 2011: PsiOxus Therapeutics To Present Data On MT-102 At Cachexia Conference 56 Aug 02, 2011: Researchers At Columbia University Discover New Drug For Sarcopenia 57 Dec 16, 2010: Myotec Therapeutics Completes Merger With Hybrid BioSystems To Form PsiOxus Therapeutics 58 Appendix 60 Methodology 60 Coverage 60 Secondary Research 60 Primary Research 60 Expert Panel Validation 60 Contact Us 61 Disclaimer 61
List of Tables Number of Products under Development for Sarcopenia, H1 2015 8 Number of Products under Development for Sarcopenia - Comparative Analysis, H1 2015 9 Number of Products under Development by Companies, H1 2015 10 Number of Products under Investigation by Universities/Institutes, H1 2015 11 Comparative Analysis by Clinical Stage Development, H1 2015 12 Comparative Analysis by Early Stage Development, H1 2015 13 Products under Development by Companies, H1 2015 14 Products under Investigation by Universities/Institutes, H1 2015 15 Sarcopenia - Pipeline by Calzada Limited, H1 2015 16 Sarcopenia - Pipeline by Cytokinetics, Inc., H1 2015 17 Sarcopenia - Pipeline by GlaxoSmithKline plc, H1 2015 18 Sarcopenia - Pipeline by Myos Corporation, H1 2015 19 Sarcopenia - Pipeline by Neurotune AG, H1 2015 20 Sarcopenia - Pipeline by Novartis AG, H1 2015 21 Sarcopenia - Pipeline by PsiOxus Therapeutics, Ltd., H1 2015 22 Sarcopenia - Pipeline by Regeneron Pharmaceuticals, Inc., H1 2015 23 Sarcopenia - Pipeline by Sumitomo Dainippon Pharma Co., Ltd., H1 2015 24 Assessment by Monotherapy Products, H1 2015 25 Number of Products by Stage and Target, H1 2015 27 Number of Products by Stage and Mechanism of Action, H1 2015 29 Number of Products by Stage and Route of Administration, H1 2015 31 Number of Products by Stage and Molecule Type, H1 2015 33 Sarcopenia Therapeutics - Recent Pipeline Updates, H1 2015 50 Sarcopenia - Dormant Projects, H1 2015 53 Sarcopenia - Discontinued Products, H1 2015 54
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