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Post-Traumatic Stress Disorder (PTSD) - Pipeline Review, H2 2015

Oct 21, 2015 | 128 Pages | Global Markets Direct | Pharmaceuticals & Healthcare

Post-Traumatic Stress Disorder (PTSD) - Pipeline Review, H2 2015

Summary

Global Markets Direct's, 'Post-Traumatic Stress Disorder (PTSD) - Pipeline Review, H2 2015', provides an overview of the Post-Traumatic Stress Disorder (PTSD)'s therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Post-Traumatic Stress Disorder (PTSD), complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Post-Traumatic Stress Disorder (PTSD) and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

- The report provides a snapshot of the global therapeutic landscape of Post-Traumatic Stress Disorder (PTSD)
- The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities 
- The report reviews key players involved in the therapeutics development for Post-Traumatic Stress Disorder (PTSD) and enlists all their major and minor projects
- The report summarizes all the dormant and discontinued pipeline projects 
- A review of the Post-Traumatic Stress Disorder (PTSD) products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- A detailed assessment of monotherapy and combination therapy pipeline projects
- Coverage of the Post-Traumatic Stress Disorder (PTSD) pipeline on the basis of target, MoA, route of administration and molecule type
- Latest news and deals relating related to pipeline products

Reasons to Buy

- Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Develop strategic initiatives by understanding the focus areas of leading companies
- Identify and understand important and diverse types of therapeutics under development for Post-Traumatic Stress Disorder (PTSD)
- Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
- Devise corrective measures for pipeline projects by understanding Post-Traumatic Stress Disorder (PTSD) pipeline depth and focus of Indication therapeutics
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and Scope
- Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
 Table of Contents
Table of Contents
2 List of Tables 7 List of Figures 8 Introduction 9 Global Markets Direct Report Coverage 9 Post-Traumatic Stress Disorder (PTSD) Overview 10 Therapeutics Development 11 Pipeline Products for Post-Traumatic Stress Disorder (PTSD) - Overview 11 Pipeline Products for Post-Traumatic Stress Disorder (PTSD) - Comparative Analysis 12 Post-Traumatic Stress Disorder (PTSD) - Therapeutics under Development by Companies 13 Post-Traumatic Stress Disorder (PTSD) - Therapeutics under Investigation by Universities/Institutes 15 Post-Traumatic Stress Disorder (PTSD) - Pipeline Products Glance 16 Late Stage Products 16 Clinical Stage Products 17 Early Stage Products 18 Unknown Stage Products 19 Post-Traumatic Stress Disorder (PTSD) - Products under Development by Companies 20 Post-Traumatic Stress Disorder (PTSD) - Products under Investigation by Universities/Institutes 22 Post-Traumatic Stress Disorder (PTSD) - Companies Involved in Therapeutics Development 23 Addex Therapeutics Ltd 23 Azevan Pharmaceuticals, Inc. 24 Catalyst Pharmaceutical Partners, Inc. 25 Eli Lilly and Company 26 HolsboerMaschmeyer NeuroChemie GmbH 27 Humanetics Corporation 28 Intra-Cellular Therapies, Inc. 29 Marinus Pharmaceuticals, Inc. 30 Neuralstem, Inc. 31 Neurocrine Biosciences, Inc. 32 NeuroNascent, Inc. 33 Omeros Corporation 34 Otsuka Holdings Co., Ltd. 35 Pfizer Inc. 36 Polleo Pharma Limited 37 Synchroneuron Inc. 38 Tonix Pharmaceuticals Holding Corp. 39 Vanda Pharmaceuticals Inc. 40 Post-Traumatic Stress Disorder (PTSD) - Therapeutics Assessment 41 Assessment by Monotherapy Products 41 Assessment by Target 42 Assessment by Mechanism of Action 44 Assessment by Route of Administration 46 Assessment by Molecule Type 48 Drug Profiles 50 acamprosate calcium SR - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 ADX-71743 - Drug Profile 52 Product Description 52 Mechanism of Action 52 R&D Progress 52 AM-3506 - Drug Profile 53 Product Description 53 Mechanism of Action 53 R&D Progress 53 brexpiprazole - Drug Profile 54 Product Description 54 Mechanism of Action 54 R&D Progress 54 CPP-115 - Drug Profile 57 Product Description 57 Mechanism of Action 57 R&D Progress 57 Drug for Post-Traumatic Stress Disorders - Drug Profile 59 Product Description 59 Mechanism of Action 59 R&D Progress 59 Drugs to Inhibit FAAH for CNS Disorders - Drug Profile 60 Product Description 60 Mechanism of Action 60 R&D Progress 60 Drugs to Modulate NPSR for Anxiety Disorder - Drug Profile 61 Product Description 61 Mechanism of Action 61 R&D Progress 61 ganaxolone - Drug Profile 62 Product Description 62 Mechanism of Action 62 R&D Progress 62 HL-9001 - Drug Profile 64 Product Description 64 Mechanism of Action 64 R&D Progress 64 IC-87201 - Drug Profile 65 Product Description 65 Mechanism of Action 65 R&D Progress 65 iloperidone - Drug Profile 66 Product Description 66 Mechanism of Action 66 R&D Progress 66 ITI-007 - Drug Profile 68 Product Description 68 Mechanism of Action 68 R&D Progress 68 NNI-351 - Drug Profile 70 Product Description 70 Mechanism of Action 70 R&D Progress 70 NSI-189 - Drug Profile 71 Product Description 71 Mechanism of Action 71 R&D Progress 71 PF-04457845 - Drug Profile 73 Product Description 73 Mechanism of Action 73 R&D Progress 73 Rycal - Drug Profile 74 Product Description 74 Mechanism of Action 74 R&D Progress 74 S-107 - Drug Profile 75 Product Description 75 Mechanism of Action 75 R&D Progress 75 Small Molecule to Target GPR151 for CNS Diseases - Drug Profile 76 Product Description 76 Mechanism of Action 76 R&D Progress 76 Small Molecule to Target GPR83 for CNS and Immunological Disorders - Drug Profile 77 Product Description 77 Mechanism of Action 77 R&D Progress 77 Small Molecules for Post-Traumatic Stress Disorder - Drug Profile 78 Product Description 78 Mechanism of Action 78 R&D Progress 78 Small Molecules to Activate TrkB Receptor for Central Nervous System, Metabolic Disorders and ENT Disorders - Drug Profile 79 Product Description 79 Mechanism of Action 79 R&D Progress 79 Small Molecules to Antagonize mGluR7 For Central Nervous System Disorders - Drug Profile 81 Product Description 81 Mechanism of Action 81 R&D Progress 81 Small Molecules to Antagonize mGluR7 for Post-Traumatic Stress Disorders and Acute Stress Disorder - Drug Profile 82 Product Description 82 Mechanism of Action 82 R&D Progress 82 Small Molecules to Antagonize TLR-4 for CNS Disorders - Drug Profile 83 Product Description 83 Mechanism of Action 83 R&D Progress 83 SRX-246 - Drug Profile 84 Product Description 84 Mechanism of Action 84 R&D Progress 84 TNX-102 - Drug Profile 86 Product Description 86 Mechanism of Action 86 R&D Progress 86 Vaccine for Post-Traumatic Stress Disorder and Depression - Drug Profile 88 Product Description 88 Mechanism of Action 88 R&D Progress 88 verucerfont - Drug Profile 89 Product Description 89 Mechanism of Action 89 R&D Progress 89 vigabatrin - Drug Profile 91 Product Description 91 Mechanism of Action 91 R&D Progress 91 ZL-006 - Drug Profile 94 Product Description 94 Mechanism of Action 94 R&D Progress 94 Post-Traumatic Stress Disorder (PTSD) - Recent Pipeline Updates 95 Post-Traumatic Stress Disorder (PTSD) - Dormant Projects 120 Post-Traumatic Stress Disorder (PTSD) - Discontinued Products 121 Post-Traumatic Stress Disorder (PTSD) - Product Development Milestones 122 Featured News & Press Releases 122 Aug 18, 2015: Tonix Pharmaceuticals Presents on the Development of TNX-102 SL for Post-Traumatic Stress Disorder (PTSD) at the 2015 Military Health System Research Symposium 122 May 26, 2015: Tonix Pharmaceuticals Announces Acceptance of Two Abstracts for Presentation at EULAR 122 May 15, 2015: Tonix Pharmaceuticals Presents Data at the Annual Meeting of the Society for Biological Psychiatry 122 Jan 15, 2015: Tonix Pharmaceuticals Commences Phase 2 Trial of TNX-102 SL in Post-Traumatic Stress Disorder 123 Jun 10, 2014: Tonix Pharmaceuticals Receives IND Clearance From U.S. Food and Drug Administration for TNX-102 SL in Post-Traumatic Stress Disorder 123 Oct 11, 2013: Tonix Pharmaceuticals to Participate in the Women's Healthcare Innovation and Leadership Showcase on October 15, 2013 124 Aug 19, 2013: Tonix Pharmaceuticals Presents Nonclinical Results at the Ninth World Congress on Myofascial Pain Syndrome and Fibromyalgia Syndrome 124 Oct 24, 2012: Tonix Pharma Completes Pre-IND Meeting With FDA For Potential New Treatment For Post-Traumatic Stress Disorder 125 Oct 15, 2012: Indiana University Scientists Identify New Compound That Could Prevent Post-Traumatic Stress Disorder 125 Oct 15, 2012: Indiana University Scientists Discover New Drug For Preventing Post-Traumatic Stress Disorder 126 Appendix 127 Methodology 127 Coverage 127 Secondary Research 127 Primary Research 127 Expert Panel Validation 127 Contact Us 127 Disclaimer 128
List of Tables
Number of Products under Development for Post-Traumatic Stress Disorder (PTSD), H2 2015 11 Number of Products under Development for Post-Traumatic Stress Disorder (PTSD) - Comparative Analysis, H2 2015 12 Number of Products under Development by Companies, H2 2015 14 Number of Products under Investigation by Universities/Institutes, H2 2015 15 Comparative Analysis by Late Stage Development, H2 2015 16 Comparative Analysis by Clinical Stage Development, H2 2015 17 Comparative Analysis by Early Stage Development, H2 2015 18 Comparative Analysis by Unknown Stage Development, H2 2015 19 Products under Development by Companies, H2 2015 20 Products under Development by Companies, H2 2015 (Contd..1) 21 Products under Investigation by Universities/Institutes, H2 2015 22 Post-Traumatic Stress Disorder (PTSD) - Pipeline by Addex Therapeutics Ltd, H2 2015 23 Post-Traumatic Stress Disorder (PTSD) - Pipeline by Azevan Pharmaceuticals, Inc., H2 2015 24 Post-Traumatic Stress Disorder (PTSD) - Pipeline by Catalyst Pharmaceutical Partners, Inc., H2 2015 25 Post-Traumatic Stress Disorder (PTSD) - Pipeline by Eli Lilly and Company, H2 2015 26 Post-Traumatic Stress Disorder (PTSD) - Pipeline by HolsboerMaschmeyer NeuroChemie GmbH, H2 2015 27 Post-Traumatic Stress Disorder (PTSD) - Pipeline by Humanetics Corporation, H2 2015 28 Post-Traumatic Stress Disorder (PTSD) - Pipeline by Intra-Cellular Therapies, Inc., H2 2015 29 Post-Traumatic Stress Disorder (PTSD) - Pipeline by Marinus Pharmaceuticals, Inc., H2 2015 30 Post-Traumatic Stress Disorder (PTSD) - Pipeline by Neuralstem, Inc., H2 2015 31 Post-Traumatic Stress Disorder (PTSD) - Pipeline by Neurocrine Biosciences, Inc., H2 2015 32 Post-Traumatic Stress Disorder (PTSD) - Pipeline by NeuroNascent, Inc., H2 2015 33 Post-Traumatic Stress Disorder (PTSD) - Pipeline by Omeros Corporation, H2 2015 34 Post-Traumatic Stress Disorder (PTSD) - Pipeline by Otsuka Holdings Co., Ltd., H2 2015 35 Post-Traumatic Stress Disorder (PTSD) - Pipeline by Pfizer Inc., H2 2015 36 Post-Traumatic Stress Disorder (PTSD) - Pipeline by Polleo Pharma Limited, H2 2015 37 Post-Traumatic Stress Disorder (PTSD) - Pipeline by Synchroneuron Inc., H2 2015 38 Post-Traumatic Stress Disorder (PTSD) - Pipeline by Tonix Pharmaceuticals Holding Corp., H2 2015 39 Post-Traumatic Stress Disorder (PTSD) - Pipeline by Vanda Pharmaceuticals Inc., H2 2015 40 Assessment by Monotherapy Products, H2 2015 41 Number of Products by Stage and Target, H2 2015 43 Number of Products by Stage and Mechanism of Action, H2 2015 45 Number of Products by Stage and Route of Administration, H2 2015 47 Number of Products by Stage and Molecule Type, H2 2015 49 Post-Traumatic Stress Disorder (PTSD) Therapeutics - Recent Pipeline Updates, H2 2015 95 Post-Traumatic Stress Disorder (PTSD) - Dormant Projects, H2 2015 120 Post-Traumatic Stress Disorder (PTSD) - Discontinued Products, H2 2015 121


List of Figures
Number of Products under Development for Post-Traumatic Stress Disorder (PTSD), H2 2015 11 Number of Products under Development for Post-Traumatic Stress Disorder (PTSD) - Comparative Analysis, H2 2015 12 Number of Products under Development by Companies, H2 2015 13 Number of Products under Investigation by Universities/Institutes, H2 2015 15 Comparative Analysis by Clinical Stage Development, H2 2015 17 Comparative Analysis by Early Stage Products, H2 2015 18 Assessment by Monotherapy Products, H2 2015 41 Number of Products by Top 10 Targets, H2 2015 42 Number of Products by Stage and Top 10 Targets, H2 2015 42 Number of Products by Top 10 Mechanism of Actions, H2 2015 44 Number of Products by Stage and Top 10 Mechanism of Actions, H2 2015 44 Number of Products by Top 10 Routes of Administration, H2 2015 46 Number of Products by Stage and Top 10 Routes of Administration, H2 2015 46 Number of Products by Top 10 Molecule Types, H2 2015 48 Number of Products by Stage and Top 10 Molecule Types, H2 2015 48

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