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Neurofibromatoses Type I (Von Recklinghausen's Disease) - Pipeline Review, H2 2016

Published: Dec, 2016 | Pages: 42 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)

Neurofibromatoses Type I (Von Recklinghausen's Disease) - Pipeline Review, H2 2016

Summary

Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Neurofibromatoses Type I - Pipeline Review, H2 2016, provides an overview of the Neurofibromatoses Type I (Genetic Disorders) pipeline landscape.

Neurofibromatosis type 1 (NF1), also called von Recklinghausen's disease, is a rare genetic disorder characterized by the development of multiple noncancerous (benign) tumors of nerves and skin (neurofibromas). This is transmitted on chromosome 17 and is caused by mutation of the NF1 gene. Symptoms include liver enlargement, glioma, Lisch nodules and pheochromocytoma. Treatment includes pain medications, surgery, chemotherapy and radiation therapy. 

Report Highlights

Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Neurofibromatoses Type I - Pipeline Review, H2 2016, provides comprehensive information on the therapeutics under development for Neurofibromatoses Type I (Genetic Disorders), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Neurofibromatoses Type I (Genetic Disorders) pipeline guide also reviews of key players involved in therapeutic development for Neurofibromatoses Type I (Von Recklinghausen's Disease) and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Phase II, Preclinical and Discovery stages are 1, 2 and 1 respectively. Similarly, the Universities portfolio in Discovery stages comprises 1 molecules, respectively.

Neurofibromatoses Type I (Genetic Disorders) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

- The pipeline guide provides a snapshot of the global therapeutic landscape of Neurofibromatoses Type I (Genetic Disorders).
- The pipeline guide reviews pipeline therapeutics for Neurofibromatoses Type I (Genetic Disorders) by companies and universities/research institutes based on information derived from company and industry-specific sources. 
- The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
- The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
- The pipeline guide reviews key companies involved in Neurofibromatoses Type I (Genetic Disorders) therapeutics and enlists all their major and minor projects.
- The pipeline guide evaluates Neurofibromatoses Type I (Genetic Disorders) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
- The pipeline guide encapsulates all the dormant and discontinued pipeline projects. 
- The pipeline guide reviews latest news related to pipeline therapeutics for Neurofibromatoses Type I (Genetic Disorders)

Reasons To Buy

- Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
- Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
- Find and recognize significant and varied types of therapeutics under development for Neurofibromatoses Type I (Genetic Disorders).
- Classify potential new clients or partners in the target demographic.
- Develop tactical initiatives by understanding the focus areas of leading companies.
- Plan mergers and acquisitions meritoriously by identifying key players and it's most promising pipeline therapeutics.
- Formulate corrective measures for pipeline projects by understanding Neurofibromatoses Type I (Genetic Disorders) pipeline depth and focus of Indication therapeutics.
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
- Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.
 Table of Contents
Table of Contents 2 List of Tables 3 List of Figures 4 Introduction 5 Global Markets Direct Report Coverage 5 Neurofibromatoses Type I (Von Recklinghausen's Disease) Overview 6 Therapeutics Development 7 Pipeline Products for Neurofibromatoses Type I (Von Recklinghausen's Disease) - Overview 7 Pipeline Products for Neurofibromatoses Type I (Von Recklinghausen's Disease) - Comparative Analysis 8 Neurofibromatoses Type I (Von Recklinghausen's Disease) - Therapeutics under Development by Companies 9 Neurofibromatoses Type I (Von Recklinghausen's Disease) - Therapeutics under Investigation by Universities/Institutes 10 Neurofibromatoses Type I (Von Recklinghausen's Disease) - Pipeline Products Glance 11 Clinical Stage Products 11 Early Stage Products 12 Neurofibromatoses Type I (Von Recklinghausen's Disease) - Products under Development by Companies 13 Neurofibromatoses Type I (Von Recklinghausen's Disease) - Products under Investigation by Universities/Institutes 14 Neurofibromatoses Type I (Von Recklinghausen's Disease) - Companies Involved in Therapeutics Development 15 Alexion Pharmaceuticals Inc 15 AstraZeneca Plc 16 Celldex Therapeutics Inc 17 Neurofibromatoses Type I (Von Recklinghausen's Disease) - Therapeutics Assessment 18 Assessment by Monotherapy Products 18 Assessment by Target 19 Assessment by Mechanism of Action 21 Assessment by Route of Administration 23 Assessment by Molecule Type 25 Drug Profiles 27 asfotase alfa - Drug Profile 27 Product Description 27 Mechanism Of Action 27 R&D Progress 27 CDX-0158 - Drug Profile 31 Product Description 31 Mechanism Of Action 31 R&D Progress 31 selumetinib sulfate - Drug Profile 33 Product Description 33 Mechanism Of Action 33 R&D Progress 33 Small Molecules for Neurofibromatoses Type I - Drug Profile 38 Product Description 38 Mechanism Of Action 38 R&D Progress 38 VAL-0524 - Drug Profile 39 Product Description 39 Mechanism Of Action 39 R&D Progress 39 Neurofibromatoses Type I (Von Recklinghausen's Disease) - Dormant Projects 40 Appendix 41 Methodology 41 Coverage 41 Secondary Research 41 Primary Research 41 Expert Panel Validation 41 Contact Us 41 Disclaimer 42
List of Tables
Number of Products under Development for Neurofibromatoses Type I (Von Recklinghausen's Disease), H2 2016 7 Number of Products under Development for Neurofibromatoses Type I (Von Recklinghausen's Disease) - Comparative Analysis, H2 2016 8 Number of Products under Development by Companies, H2 2016 9 Number of Products under Investigation by Universities/Institutes, H2 2016 10 Comparative Analysis by Clinical Stage Development, H2 2016 11 Comparative Analysis by Early Stage Development, H2 2016 12 Products under Development by Companies, H2 2016 13 Products under Investigation by Universities/Institutes, H2 2016 14 Neurofibromatoses Type I (Von Recklinghausen's Disease) - Pipeline by Alexion Pharmaceuticals Inc, H2 2016 15 Neurofibromatoses Type I (Von Recklinghausen's Disease) - Pipeline by AstraZeneca Plc, H2 2016 16 Neurofibromatoses Type I (Von Recklinghausen's Disease) - Pipeline by Celldex Therapeutics Inc, H2 2016 17 Assessment by Monotherapy Products, H2 2016 18 Number of Products by Stage and Target, H2 2016 20 Number of Products by Stage and Mechanism of Action, H2 2016 22 Number of Products by Stage and Route of Administration, H2 2016 24 Number of Products by Stage and Molecule Type, H2 2016 26 Neurofibromatoses Type I (Von Recklinghausen's Disease) - Dormant Projects, H2 2016 40



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