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Published: Jan, 2015 | Pages:
74 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Intermittent Claudication - Pipeline Review, H1 2015 Summary Global Markets Direct's, 'Intermittent Claudication - Pipeline Review, H1 2015', provides an overview of the Intermittent Claudication's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Intermittent Claudication, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Intermittent Claudication and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Intermittent Claudication - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Intermittent Claudication and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Intermittent Claudication products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Intermittent Claudication pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons To Buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Intermittent Claudication - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Intermittent Claudication pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 4 List of Figures 5 Introduction 6 Global Markets Direct Report Coverage 6 Intermittent Claudication Overview 7 Therapeutics Development 8 Pipeline Products for Intermittent Claudication - Overview 8 Pipeline Products for Intermittent Claudication - Comparative Analysis 9 Intermittent Claudication - Therapeutics under Development by Companies 10 Intermittent Claudication - Pipeline Products Glance 11 Clinical Stage Products 11 Early Stage Products 12 Intermittent Claudication - Products under Development by Companies 13 Intermittent Claudication - Companies Involved in Therapeutics Development 14 Cytokinetics, Inc. 14 DNAVEC Corporation 15 Genovate Biotechnology Co., LTD. 16 Kowa Company, Ltd. 17 LTT Bio-Pharma Co., Ltd. 18 Nuo Therapeutics, Inc. 19 Pluristem Therapeutics Inc. 20 Rigel Pharmaceuticals, Inc. 21 Taisho Toyama Pharmaceutical Co., Ltd. 22 Intermittent Claudication - Therapeutics Assessment 23 Assessment by Monotherapy Products 23 Assessment by Target 24 Assessment by Mechanism of Action 26 Assessment by Route of Administration 28 Assessment by Molecule Type 30 Drug Profiles 32 ALD-301 - Drug Profile 32 Product Description 32 Mechanism of Action 32 R&D Progress 32 alprostadil - Drug Profile 34 Product Description 34 Mechanism of Action 34 R&D Progress 34 cilostazol CR - Drug Profile 35 Product Description 35 Mechanism of Action 35 R&D Progress 35 CK-2066260 - Drug Profile 36 Product Description 36 Mechanism of Action 36 R&D Progress 36 DVC1-0101 - Drug Profile 38 Product Description 38 Mechanism of Action 38 R&D Progress 38 ecraprost - Drug Profile 39 Product Description 39 Mechanism of Action 39 R&D Progress 39 K-134 - Drug Profile 41 Product Description 41 Mechanism of Action 41 R&D Progress 41 LT-0101 - Drug Profile 42 Product Description 42 Mechanism of Action 42 R&D Progress 42 R-118 - Drug Profile 43 Product Description 43 Mechanism of Action 43 R&D Progress 43 Stem Cell Therapy for Cardiovascular Diseases - Drug Profile 44 Product Description 44 Mechanism of Action 44 R&D Progress 44 tirasemtiv - Drug Profile 46 Product Description 46 Mechanism of Action 46 R&D Progress 46 Intermittent Claudication - Recent Pipeline Updates 53 Intermittent Claudication - Dormant Projects 65 Intermittent Claudication - Discontinued Products 66 Intermittent Claudication - Product Development Milestones 67 Featured News & Press Releases 67 Mar 06, 2014: Rigel Announces Publication of R118 AMPK Activator Research 67 Nov 13, 2013: Pluristem Receives Regulatory Approval to Extend Its Phase II Study of PLX-PAD Cells in the Treatment of Intermittent Claudication to South Korea 68 Oct 02, 2013: Pluristem Receives Israeli Ministry of Health Approval to Expand Its Phase II Clinical Trial in Intermittent Claudication to Israel 68 Sep 16, 2013: FDA Lifts Clinical Hold of Pluristem's Phase II Intermittent Claudication Study 69 Jul 08, 2013: Pluristem's South Korean Partner Files IND With Korean FDA for PLX Cells 69 Jun 04, 2013: Pluristem To Receive Clinical-hold Notice From FDA For US Phase II Intermittent Claudication Study 69 Jan 15, 2013: Pluristem Receives Approval To Expand Phase II Clinical Trial In Intermittent Claudication To Germany 70 Aug 23, 2012: Pluristem Commences Phase II Clinical Trial For Intermittent Claudication Using PLX Cells 70 Aug 13, 2012: Pluristem Moves Intermittent Claudication Indication Forward in Germany Through Collaboration With Cato Research 71 Jul 18, 2012: Pluristem Partners With CPC Clinical Research For Peripheral Artery Disease Study 71 Appendix 73 Methodology 73 Coverage 73 Secondary Research 73 Primary Research 73 Expert Panel Validation 73 Contact Us 74 Disclaimer 74
List of Tables Number of Products under Development for Intermittent Claudication, H1 2015 8 Number of Products under Development for Intermittent Claudication - Comparative Analysis, H1 2015 9 Number of Products under Development by Companies, H1 2015 10 Comparative Analysis by Clinical Stage Development, H1 2015 11 Comparative Analysis by Early Stage Development, H1 2015 12 Products under Development by Companies, H1 2015 13 Intermittent Claudication - Pipeline by Cytokinetics, Inc., H1 2015 14 Intermittent Claudication - Pipeline by DNAVEC Corporation, H1 2015 15 Intermittent Claudication - Pipeline by Genovate Biotechnology Co., LTD., H1 2015 16 Intermittent Claudication - Pipeline by Kowa Company, Ltd., H1 2015 17 Intermittent Claudication - Pipeline by LTT Bio-Pharma Co., Ltd., H1 2015 18 Intermittent Claudication - Pipeline by Nuo Therapeutics, Inc., H1 2015 19 Intermittent Claudication - Pipeline by Pluristem Therapeutics Inc., H1 2015 20 Intermittent Claudication - Pipeline by Rigel Pharmaceuticals, Inc., H1 2015 21 Intermittent Claudication - Pipeline by Taisho Toyama Pharmaceutical Co., Ltd., H1 2015 22 Assessment by Monotherapy Products, H1 2015 23 Number of Products by Stage and Target, H1 2015 25 Number of Products by Stage and Mechanism of Action, H1 2015 27 Number of Products by Stage and Route of Administration, H1 2015 29 Number of Products by Stage and Molecule Type, H1 2015 31 Intermittent Claudication Therapeutics - Recent Pipeline Updates, H1 2015 53 Intermittent Claudication - Dormant Projects, H1 2015 65 Intermittent Claudication - Discontinued Products, H1 2015 66
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