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Essential Thrombocythemia - Pipeline Review, H2 2016

Published: Oct, 2016 | Pages: 82 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)

Essential Thrombocythemia - Pipeline Review, H2 2016

Summary

Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Essential Thrombocythemia - Pipeline Review, H2 2016, provides an overview of the Essential Thrombocythemia (Oncology) pipeline landscape.

Essential thrombocythemia is a chronic myeloproliferative neoplasm in which cells in the bone marrow that produce the blood cells develop and function abnormally. In essential thrombocythemia, there is mainly an overproduction of platelet forming cells (megakaryocytes) in the marrow. Symptoms of essential thrombocythemia include headache, dizziness, weakness or numbness on one side of the body, slurred speech and transient ischemic attacks. 

Report Highlights

Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Essential Thrombocythemia - Pipeline Review, H2 2016, provides comprehensive information on the therapeutics under development for Essential Thrombocythemia (Oncology), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Essential Thrombocythemia (Oncology) pipeline guide also reviews of key players involved in therapeutic development for Essential Thrombocythemia and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Phase III, Phase II and Phase I stages are 3, 6 and 1 respectively for Essential Thrombocythemia.

Essential Thrombocythemia (Oncology) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

- The pipeline guide provides a snapshot of the global therapeutic landscape of Essential Thrombocythemia (Oncology).
- The pipeline guide reviews pipeline therapeutics for Essential Thrombocythemia (Oncology) by companies and universities/research institutes based on information derived from company and industry-specific sources. 
- The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
- The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
- The pipeline guide reviews key companies involved in Essential Thrombocythemia (Oncology) therapeutics and enlists all their major and minor projects.
- The pipeline guide evaluates Essential Thrombocythemia (Oncology) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
- The pipeline guide encapsulates all the dormant and discontinued pipeline projects. 
- The pipeline guide reviews latest news related to pipeline therapeutics for Essential Thrombocythemia (Oncology)

Reasons To Buy

- Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
- Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
- Find and recognize significant and varied types of therapeutics under development for Essential Thrombocythemia (Oncology).
- Classify potential new clients or partners in the target demographic.
- Develop tactical initiatives by understanding the focus areas of leading companies.
- Plan mergers and acquisitions meritoriously by identifying key players and it's most promising pipeline therapeutics.
- Formulate corrective measures for pipeline projects by understanding Essential Thrombocythemia (Oncology) pipeline depth and focus of Indication therapeutics.
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
- Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.
 Table of Contents
Table of Contents 2 List of Tables 4 List of Figures 5 Introduction 6 Global Markets Direct Report Coverage 6 Essential Thrombocythemia Overview 7 Therapeutics Development 8 Pipeline Products for Essential Thrombocythemia - Overview 8 Essential Thrombocythemia - Therapeutics under Development by Companies 9 Essential Thrombocythemia - Pipeline Products Glance 10 Late Stage Products 10 Clinical Stage Products 11 Essential Thrombocythemia - Products under Development by Companies 12 Essential Thrombocythemia - Companies Involved in Therapeutics Development 13 Aop Orphan Pharmaceuticals AG 13 F. Hoffmann-La Roche Ltd. 14 Galena Biopharma, Inc. 15 Gilead Sciences, Inc. 16 Incyte Corporation 17 Italfarmaco S.p.A. 18 MEI Pharma, Inc. 19 Novartis AG 20 PharmaEssentia Corporation 21 Essential Thrombocythemia - Therapeutics Assessment 22 Assessment by Monotherapy Products 22 Assessment by Target 23 Assessment by Mechanism of Action 25 Assessment by Route of Administration 27 Assessment by Molecule Type 29 Drug Profiles 31 anagrelide hydrochloride CR - Drug Profile 31 Product Description 31 Mechanism Of Action 31 R&D Progress 31 anagrelide hydrochloride PR - Drug Profile 34 Product Description 34 Mechanism Of Action 34 R&D Progress 34 givinostat - Drug Profile 35 Product Description 35 Mechanism Of Action 35 R&D Progress 35 momelotinib dihydrochloride - Drug Profile 37 Product Description 37 Mechanism Of Action 37 R&D Progress 37 peginterferon alfa-2a - Drug Profile 42 Product Description 42 Mechanism Of Action 42 R&D Progress 42 pracinostat - Drug Profile 43 Product Description 43 Mechanism Of Action 43 R&D Progress 43 ropeginterferon alfa-2b - Drug Profile 48 Product Description 48 Mechanism Of Action 48 R&D Progress 48 ruxolitinib phosphate - Drug Profile 50 Product Description 50 Mechanism Of Action 50 R&D Progress 50 sonidegib phosphate - Drug Profile 63 Product Description 63 Mechanism Of Action 63 R&D Progress 63 vismodegib - Drug Profile 67 Product Description 67 Mechanism Of Action 67 R&D Progress 67 Essential Thrombocythemia - Dormant Projects 73 Essential Thrombocythemia - Discontinued Products 74 Essential Thrombocythemia - Product Development Milestones 75 Featured News & Press Releases 75 Sep 12, 2016: Galena Biopharma Expands GALE-401 Intellectual Property Protection with Patent Issuance in Japan 75 Jun 13, 2016: Galena Biopharma Presents GALE-401 Combined Safety Data at the European Hematology Association 21st Congress 75 Nov 18, 2014: Galena Biopharma Completes Enrollment In GALE-401 (Anagrelide Controlled Release) Phase 2 Clinical Trial 76 Feb 13, 2013: Novartis's Myelofibrosis Drug Jakavi Turned Down By NICE In Draft Guidance 77 May 31, 2011: YM BioSciences Announces Orphan Drug Designation For JAK1/JAK2 Inhibitor CYT387 In Europe 78 Dec 06, 2010: Incyte Presents Positive Phase II Trial Results Of INCB18424 In Advanced Polycythemia Vera And Essential Thrombocythemia At ASH Annual Meeting 78 May 28, 2009: Incyte Provides Update on Special Protocol Assessment for INCB18424 As A New Treatment for Myelofibrosis 80 Appendix 81 Methodology 81 Coverage 81 Secondary Research 81 Primary Research 81 Expert Panel Validation 81 Contact Us 81 Disclaimer 82
List of Tables
Number of Products under Development for Essential Thrombocythemia, H2 2016 8 Number of Products under Development by Companies, H2 2016 9 Comparative Analysis by Late Stage Development, H2 2016 10 Comparative Analysis by Clinical Stage Development, H2 2016 11 Products under Development by Companies, H2 2016 12 Essential Thrombocythemia - Pipeline by Aop Orphan Pharmaceuticals AG, H2 2016 13 Essential Thrombocythemia - Pipeline by F. Hoffmann-La Roche Ltd., H2 2016 14 Essential Thrombocythemia - Pipeline by Galena Biopharma, Inc., H2 2016 15 Essential Thrombocythemia - Pipeline by Gilead Sciences, Inc., H2 2016 16 Essential Thrombocythemia - Pipeline by Incyte Corporation, H2 2016 17 Essential Thrombocythemia - Pipeline by Italfarmaco S.p.A., H2 2016 18 Essential Thrombocythemia - Pipeline by MEI Pharma, Inc., H2 2016 19 Essential Thrombocythemia - Pipeline by Novartis AG, H2 2016 20 Essential Thrombocythemia - Pipeline by PharmaEssentia Corporation, H2 2016 21 Assessment by Monotherapy Products, H2 2016 22 Number of Products by Stage and Target, H2 2016 24 Number of Products by Stage and Mechanism of Action, H2 2016 26 Number of Products by Stage and Route of Administration, H2 2016 28 Number of Products by Stage and Molecule Type, H2 2016 30 Essential Thrombocythemia - Dormant Projects, H2 2016 73 Essential Thrombocythemia - Discontinued Products, H2 2016 74



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